Local and global analysis of endocrine regulation as a non-cyclic feedback system [PDF]
, 2016 To understand the sophisticated control mechanisms of the human's endocrine system is a challenging task that is a crucial step towards precise medical treatment of many disfunctions and diseases. Although mathematical models describing the endocrine system as a whole are still elusive, recently some substantial progress has been made in analyzing ...
arxiv +1 more source
Insights into endocrine-immunological disturbances in autoimmunity and their impact on treatment [PDF]
, 2009 The neuroendocrine immune (NEI) system is regarded as a fundamental network for the maintenance of health status (homeostasis), and it plays an important role in several systemic diseases, including autoimmune disorders.
Cutolo, Maurizio, Straub, Rainer H
core +2 more sources
Thyroid Hormone Availability and Action during Brain Development in Rodents
Frontiers in Cellular Neuroscience, 2017 Thyroid hormones (THs) play an essential role in the development of all vertebrates; in particular adequate TH content is crucial for proper neurodevelopment.
Soledad Bárez-López +3 more
doaj +1 more source
Systems Biology: Identifiability analysis and parameter identification via systems-biology informed neural networks [PDF]
arXiv, 2022 The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce systems-biology informed neural networks for parameter estimation by incorporating the system of ODEs into the neural networks.
arxiv
The Adrenal Gland: Central Relay in Health and Disease [PDF]
, 2019 Diseases of the adrenal gland are as important for the general practitioner as for the endocrine specialist. The high prevalence of some adrenal endocrinopathies, such as adrenal incidentalomas (1-2% of the population) and primary aldosteronism (6% of ...
Beuschlein, Felix +6 more
core +3 more sources
New Arabic Medical Dataset for Diseases Classification [PDF]
arXiv, 2021 The Arabic language suffers from a great shortage of datasets suitable for training deep learning models, and the existing ones include general non-specialized classifications. In this work, we introduce a new Arab medical dataset, which includes two thousand medical documents collected from several Arabic medical websites, in addition to the Arab ...
arxiv
One special question to start with: can HIF/NFkB be a target in inflammation? [PDF]
, 2015 Hypoxia and Inflammation are strictly interconnected with important consequences at clinical and therapeutic level. While cell and tissue damage due to acute hypoxia mostly leads to cell necrosis, in chronic hypoxia, cells that are located closer to ...
CARNEVALE, ILARIA +8 more
core +1 more source
Protective roles of melatonin in central nervous system diseases by regulation of neural stem cells
Cell Proliferation, 2017 Neural stem cells (NSCs) are immature precursors of the central nervous system (CNS), with self‐renewal and multipotential differentiation abilities.
Xin Yu +5 more
semanticscholar +1 more source
Modulation of PC1/3 activity by a rare double-site homozygous mutation
Frontiers in Pediatrics, 2022 ObjectivesPreprotein convertase 1/3 deficiency is a rare autosomal recessive disorder in which patients present with malabsorptive diarrhea and a series of symptoms of endocrine disorders such as polydipsia, reactive hypoglycemia, growth hormone ...
Yanyan Ni +5 more
doaj +1 more source
Expert System Based On Neural-Fuzzy Rules for Thyroid Diseases Diagnosis [PDF]
, 2014 The thyroid, an endocrine gland that secretes hormones in the blood, circulates its products to all tissues of the body, where they control vital functions in every cell. Normal levels of thyroid hormone help the brain, heart, intestines, muscles and reproductive system function normally.
arxiv +1 more source