Results 51 to 60 of about 748,456 (359)
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li+10 more
wiley +1 more source
Use of interactive “Case Study” method in the training of future physicians
Last decade is characterized by rapid use of a large number of virtual technologies in the different spheres of human activity. Introduction of innovative technologies into education processes in the system of higher education is an actual problem of its
I.V. Cherniavska+3 more
doaj +1 more source
Sleep and circadian disruption are associated with an increased risk of metabolic disease, including obesity and diabetes. Mounting evidence indicates that misaligned and/or non-functional clock proteins in peripheral tissues critically contribute to the
Gabriella M. Marino, Deanna M. Arble
doaj +1 more source
Advances in endocrinology [PDF]
Molecular genetics will continue to help us to make precise diagnoses. At present, the expertise to achieve this for a specific disease is often exclusive to one unit with a research interest. It will be important to establish a coordinated approach at a supraregional level to provide molecular diagnosis for rare disorders as a fast reliable clinical ...
Clayton, Peter E., Tillmann, Vallo
openaire +4 more sources
Grid infrastructures supporting paediatric endocrinology across Europe [PDF]
Paediatric endocrinology is a highly specialised area of clinical medicine with many experts with specific knowledge distributed over a wide geographical area.
Ajayi, O., Sinnott, R.O., Stell, A.J.
core +2 more sources
CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]
The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro+15 more
core +3 more sources
Morbid Obesity Due to Prolactinoma and Significant Weight Loss After Dopamine Agonist Treatment
Objective: Morbid obesity may be related to a prolactinoma, although uncommon, and can lead to adverse effects like insulin resistance and metabolic syndrome. Recent research suggests that hyperprolactinemia causes an abnormal lipid profile, weight gain,
Muzaffar Ali, MBBS, Lubna Mirza, MD
doaj +1 more source
Cardiovascular features of possible autonomous cortisol secretion in patients with adrenal incidentalomas [PDF]
Background: Low-grade incomplete post-dexamethasone cortisol suppression in patients with adrenal incidentalomas – recently defined as possible autonomous cortisol secretion (pACS) – has been associated with increased cardiovascular events and mortality.
Di Giorgio, Maria Rosaria+12 more
core +2 more sources
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker+9 more
wiley +1 more source
Aim: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). Patients & methods: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified ...
Nina J Karlin+5 more
doaj +1 more source