Results 61 to 70 of about 811,687 (352)

Grid infrastructures supporting paediatric endocrinology across Europe [PDF]

open access: yes, 2007
Paediatric endocrinology is a highly specialised area of clinical medicine with many experts with specific knowledge distributed over a wide geographical area.
Ajayi, O., Sinnott, R.O., Stell, A.J.
core   +2 more sources

Use of interactive “Case Study” method in the training of future physicians

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2019
Last decade is characterized by rapid use of a large number of virtual technologies in the different spheres of human activity. Introduction of innovative technologies into education processes in the system of higher education is an actual problem of its
I.V. Cherniavska   +3 more
doaj   +1 more source

Assessing the relationship between institutional cancer and diabetes mortality rates using National Death Index data

open access: yesFuture Science OA, 2020
Aim: To evaluate overall survival (OS), glycemic control in cancer patients with and without diabetes mellitus (DM). Patients & methods: Patients (2010–2015) with newly diagnosed prostate, breast, lung, colorectal and pancreatic cancers were identified ...
Nina J Karlin   +5 more
doaj   +1 more source

Role of Endocrine System in the Regulation of Female Insect Reproduction

open access: yesBiology, 2021
The proper synthesis and functioning of ecdysteroids and juvenile hormones (JHs) are very important for the regulation of vitellogenesis and oogenesis.
Muhammad Zaryab Khalid   +3 more
doaj   +1 more source

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

open access: yesAdvanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen   +14 more
wiley   +1 more source

The Impact of Krebs Cycle Intermediates on the Endocrine System and Immune System: A Comparison

open access: yesEndocrines, 2023
Introduction: The Krebs cycle is an important set of reactions that synthesize different molecules and substances that affect various organs. The objective of this paper was to compare the effects of Krebs cycle intermediates on the endocrine system and ...
Borros M. Arneth
doaj   +1 more source

Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]

open access: yes, 2009
Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bamshad   +46 more
core   +1 more source

CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target

open access: yesAdvanced Science, EarlyView.
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo   +15 more
wiley   +1 more source

Intestinal permeability is associated with aggravated inflammation and myofibroblast accumulation in Graves’ orbitopathy: the MicroGO study

open access: yesFrontiers in Endocrinology, 2023
BackgroundGraves’ disease (GD) and Graves’ orbitopathy (GO) result from ongoing stimulation of the TSH receptor due to autoantibodies acting as persistent agonists.
Aline C. Fenneman   +11 more
doaj   +1 more source

CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]

open access: yes, 2018
The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro   +15 more
core   +3 more sources

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