Results 61 to 70 of about 784,305 (383)

Update on male reproductive endocrinology. [PDF]

, 2018
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
core   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Development and evaluation of a health‐related quality‐of‐life tool for dogs with Cushing's syndrome

Journal of Veterinary Internal Medicine, 2019
Background Clinical signs and consequences of Cushing's syndrome are likely to impact upon a dog's life. Quantification of this impact on a dog's health‐related quality‐of‐life (HRQoL) could contribute to optimized disease management.
Imogen Schofield, Dan G. O'Neill, Dave C. Brodbelt, David B. Church, Rebecca F. Geddes, Stijn J. M. Niessen   +5 more
doaj   +1 more source

Quantification of metformin and glyburide in blood for paediatric endocrinology

Acta Pediátrica de México, 2014
Background: The recent use of antidiabetic drugs such as metformin and glyburide for the treatment and control of childhood obesity, insulin resistance and type II diabetes mellitus in children and adolescents, has encouraged physicians to determine ...
Radamés Alemón-Medina, Juan Luis Chávez-Pacheco, Blanca Ramírez-Mendiola, Liliana Rivera-Espinosa, Raquel García-Álvarez   +4 more
doaj   +1 more source

Sex differences in the pituitary TGFβ1 system: the role of TGFβ1 in prolactinoma development [PDF]

, 2019
Prolactinomas are the most frequent functioning pituitary adenomas, and sex differences in tumor size, behavior and incidence have been described. These differences have been associated with earlier diagnosis in woman, as well as with serum estradiol ...
Abeledo Machado, Alejandra Inés, Camilletti, María Andrea, Diaz, Graciela Susana, Faraoni, Erika Yanil, Ratner, Laura Daniela, Recouvreux, Maria Victoria, Rulli, Susana Beatriz   +6 more
core   +1 more source

European Society of Endocrinology Clinical Practice Guideline for long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma.

European Journal of Endocrinology, 2016
Phaeochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumours. Standard treatment is surgical resection. Following complete resection of the primary tumour, patients with PPGL are at risk of developing new tumoural events.
P. Plouin, L. Amar, O. Dekkers, M. Fassnacht, A. Gimenez-Roqueplo, J. Lenders, Charlotte Lussey-Lepoutre, O. Steichen   +7 more
semanticscholar   +1 more source

ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of Cushing's syndrome

European Journal of Endocrinology, 2020
Clinical evaluation should guide those needing immediate investigation. Strict adherence to COVID-19 protection measures is necessary. Alternative ways of consultations (telephone, video) should be used.
J. Newell-Price, L. Nieman, M. Reincke, A. Tabarin   +3 more
semanticscholar   +1 more source

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

Advanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo, Kexin Tong, Yeting Gan, Min Tang, Yuguo Niu, Kan Liu, Shihong Ni, Shangming Wu, Xiaoxue Jiang, Haizhou Jiang, Fei Xiao, Shanghai Chen, Wei Lv, Xiaoying Li, Feixiang Yuan, Feifan Guo   +15 more
wiley   +1 more source

Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016.

European Journal of Endocrinology, 2018
OBJECTIVE To collect outcome data in a large cohort of patients with aggressive pituitary tumours (APT)/carcinomas (PC) and specifically report effects of temozolomide (TMZ) treatment.
A. McCormack, O. Dekkers, S. Petersenn, V. Popović, J. Trouillas, G. Raverot, P. Burman   +6 more
semanticscholar   +1 more source

Trends in the Endocrinology Fellowship Recruitment: Reasons for Concern and Possible Interventions

Journal of Clinical Endocrinology and Metabolism, 2020
The rising prevalence of endocrine disorders over the past two decades -primarily driven by chronic conditions like diabetes- has resulted in a shortage of adult endocrinologists.
G. Romeo, I. Hirsch, R. Lash, R. Gabbay
semanticscholar   +1 more source