Results 31 to 40 of about 1,780,146 (263)

iNKT Cells and Their potential Lipid Ligands during Viral Infection

Frontiers in Immunology, 2015
Invariant natural killer T (iNKT) cells are a unique population of lipid reactive CD1d restricted innate-like T lymphocytes. Despite being a minor population, they serve as an early source of cytokines and promote immunological crosstalk thus bridging ...
Anunya eOpasawatchai, Anunya eOpasawatchai, Ponpan eMatangkasombut, Ponpan eMatangkasombut   +3 more
doaj   +1 more source

Eating disorders in the structure of depressive states

European Psychiatry, 2022
Introduction Anorexia nervosa is a disease that occurs mainly in adolescent and young girls and is expressed in a conscious, extremely persistent and purposeful desire to lose weight, often reaching severe cachexia with a possible fatal outcome ...
A. Barkhatova, A. Smolnikova, S. Sorokin
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Renewable Hydrogen from Biomass: Technological Pathways and Economic Perspectives

Energies
Hydrogen is undeniably one of the most promising options for producing energy with minimal environmental impact. However, current hydrogen production is still derived from carbon-intensive processes relying on fossil fuels.
José Ramón Copa Rey, Cecilia Mateos-Pedrero, Andrei Longo, Bruna Rijo, Paulo Brito, Paulo Ferreira, Catarina Nobre   +6 more
doaj   +1 more source

Stages of treatment of eating disorders in endogenous depressions

European Psychiatry, 2023
Introduction The problem of eating disorders has become increasingly important in recent years, due to the increase in the number of cases among children and adolescents, as well as the insufficient effectiveness of therapeutic measures.
A. Barkhatova, A. Smolnikova, M. Bolgov
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Bilateral endogenous endophthalmitis – An excellent visual outcome

Kerala Journal of Ophthalmology, 2019
We report a case of a young female patient presenting with bilateral endogenous endophthalmitis (EE) following meningitis due to Neisseria meningitidis with excellent visual outcome.
Balbir Khan, Rajwinder Kaur
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

CAN DEPLOYMENT OF ATTENTION BE STRATEGICALLY CONTROLLED? [PDF]

Psihologija, 2009
The main goal of the experiment was to test whether deployment ofattention could be strategically controlled. Subjects viewed five-letter arrays.Each array included a letter unique in shape (i.e. target).
Suncica Zdravkovic, Marjena Popovic
doaj