Results 131 to 140 of about 1,477,498 (302)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Endogenous Longevity and Economic Growth [PDF]
In a two period overlapping generations model of endogenous longevity and economic growth, individuals choose to invest in health and education. The investments are costly in terms of foregone first period consumption and the benefit is in the second ...
Jocelyn E. Finlay
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Debt limits and endogenous growth. [PDF]
This paper studies the consequences on growth and welfare of imposing limits to public borrowing. In the model economy, government spending may play two different roles, either as input in the production function, or providing services directly in the ...
Blas Pérez, Beatriz de
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Heterogeneous mark-ups, growth and endogenous misallocation [PDF]
, 2013 The recent work on misallocation argues that aggregate productivity in poor countries is low because various market frictions prevent marginal products from being equalized.
Peters, Michael
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FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Financial Innovation and Endogenous Growth [PDF]
We model technological and ?nancial innovation as re?ecting the decisions of pro?t maximizing agents and explore the implications for economic growth. We start with a Schumpeterian growth model where entrepreneurs earn pro?ts by inventing better goods ...
Luc Laeven +2 more
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FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Labor Specialization and Endogenous Growth [PDF]
International Development, Labor and Human Capital,
Kim, Sunwoong, Mohtadi, Hamid
core +1 more source
Endogenous Depopulation and Economic Growth
Fertility rates have declined dramatically across almost all high-income countries over the past decades. In some countries, population growth is already negative and many more are projected to exhibit negative population growth in the coming decades. This has raised concerns about future economic prospects. Indeed, fully–endogenous and semi–endogenous
Alberto Bucci, Klaus Prettner
openaire +2 more sources