Results 171 to 180 of about 772,306 (264)

Aging, Dauer, and Stature Phenotypes Are Conferred by Structure-Directed Missense Mutations in the Endogenous AGE-1/Phosphatidylinositol 3-Kinase Catalytic Subunit. [PDF]

Aging Cell
Wu Y, Duong T, Rasmussen NR, Rossman KL, Reiner DJ.   +4 more
europepmc   +1 more source

A Naphthalimide‐Based NIR‐Emissive AIE Photosensitizer for Synergistic Apoptosis/Ferroptosis‐Mediated Antitumor Therapy and Broad‐Spectrum Bacterial Inactivation With Rapid Wound Healing

Advanced Healthcare Materials, EarlyView.
An ionic naphthalimide AIE photosensitizer (PS), TPAPV‐NIM‐M, anchors to cellular and bacterial membranes, emits in the far‐red/near‐infrared (NIR) region, and efficiently generates reactive oxygen species (ROS) under white light. Its membrane‐localized photodynamic action drives apoptosis/ferroptosis‐mediated tumor suppression and broad‐spectrum ...
Sayed Mir Sayed, Zeeshan Tahir, Fahri Alkan, Yavuz Nuri Ertas   +3 more
wiley   +1 more source

Endogenous neoantigen-specific antibodies mediate antitumor responses and determine vaccine efficacy. [PDF]

J Immunother Cancer
Sodhi SS, Wang JS, Severson DT, Ragusa JV, Moon N, Trotter T, Tsao LC, Lyerly HK, Hartman ZC.   +8 more
europepmc   +1 more source

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

Advanced Healthcare Materials, EarlyView.
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale, Nguyen Van Duc Long, Philip M. Williams, Jens Hauslage, Volker Hessel   +4 more
wiley   +1 more source

Correlative Changes in Endogenous Polyamines and Hormones Associated with Aging in Ancient <i>Cinnamomum camphora</i>. [PDF]

Plants (Basel)
Feng J, He M, Sun J, Wen X, Ye G, Feng Y, Chen Q, Wu H, El-Kassaby YA, Yang Z.   +9 more
europepmc   +1 more source

Vascularization of Human iPSC‐Derived Kidney Organoids Using Perfusion Culture, Pre‐Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix

Advanced Healthcare Materials, EarlyView.
An integrated perfusion‐based culture platform combining pre‐vascularized collagen scaffolds, stromal vascular fraction cells, and kidney decellularized extracellular matrix promotes vascularization of human iPSC‐derived kidney organoids. The platform provides evidence of interactions between vascular networks and glomerular‐like structures and enables
Helen Kearney, Andrea Mazzoleni, Ivan Martin, Lorenzo Moroni, Manuele Giuseppe Muraro, Carlos Mota   +5 more
wiley   +1 more source

Terrestrial Plant- and Algal-Derived Biostimulants as Modulators of ROS and Hormone Networks in Crop Abiotic Stress Resilience. [PDF]

Plants (Basel)
Minkov P, Gechev TS, Kanojia A.
europepmc   +1 more source

An endogenous growth pattern of roots is revealed in seedlings grown in microgravity. [PDF]

Astrobiology, 2011
Millar KD, Johnson CM, Edelmann RE, Kiss JZ.   +3 more
europepmc   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Retroviruses and Cancer: Coevolution and Genetic Exchanges Between the Viral and the Host Genomes. [PDF]

Biology (Basel)
Xia X.
europepmc   +1 more source