Results 141 to 150 of about 74,218 (327)

Ingestion of Amniotic Fluid Enhances\ud Opiate Analgesia in Rats [PDF]

open access: yes, 1986
Placenta ingestion has recently been shown to enhance opiate-mediated analgesia produced by morphine injection, footshock, or vaginal/cervical stimulation.
Abbott, Patricia   +2 more
core  

Pharmacokinetics and Safety of a Single Subcutaneous or Intramuscular Dose of Ketamine in Healthy Horses

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Pharmacokinetics (PK) of intramuscular (IM) and subcutaneous (SC) ketamine in horses has not been described. This study aimed to evaluate the PK and safety of ketamine and its metabolites after a single SC or IM administration. In Phase 1, two horses received 0.5 or 1 mg/kg of ketamine via SC and IM routes.
Ana Rangel   +5 more
wiley   +1 more source

The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia. [PDF]

open access: yesFront Syst Neurosci, 2022
Lubejko ST   +5 more
europepmc   +1 more source

Does Prolonged Naltrexone Therapy Alter the Rewarding Nature of Exercise, Socialization, and Eating? A Narrative Review

open access: yesMcGill Journal of Medicine
Introduction: Naltrexone is an opioid receptor antagonist prescribed for alcohol use disorder and opioid use disorder.  Naltrexone has a high affinity for the mu-opioid receptors, which are the primary binding site of beta-endorphin.
Caitlin Collier, Thomas Hilton
doaj   +1 more source

Dose-Dependent Enhancement of Morphine-Induced Analgesia\ud by Ingestion of Amniotic Fluid and Placenta [PDF]

open access: yes, 1988
Ingestion of amniotic fluid and placenta by rats has been shown to enhance opioid-mediated analgesia. The present studies were designed to examine the effect of several doses and volumes of placenta and amniotic fluid on tail-flick latency in rats ...
Abbott, Patricia   +2 more
core  

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

open access: yesNeurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao   +6 more
wiley   +1 more source

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