Results 201 to 210 of about 74,218 (327)

Endogenous opioid receptors and the feast or famine of maladaptive feeding. [PDF]

Nat Commun
Sutton Hickey AK, Matikainen-Ankney BA.
europepmc   +1 more source

Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function. [PDF]

Neuropsychopharmacology, 2022
Love T, Shabalin AA, Kember RL, Docherty AR, Zhou H, Koppelmans V, Gelernter J, Baker AK, Hartwell E, Dubroff J, Zubieta JK, Kranzler HR.   +11 more
europepmc   +1 more source

Evidence of Endogenous Mu Opioid Receptor Regulation by Epigenetic Control of the Promoters

, 2007
Cheol Kyu Hwang, Kyu Young Song, Chun Sung Kim, Hack Sun Choi, Xiaohong Guo, Ping‐Yee Law, Li‐Na Wei, Horace H. Loh   +7 more
openalex   +1 more source

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

A Theoretical Endogenous Opioid Neurobiological Framework for Co-occurring Pain, Trauma, and Non-suicidal Self-injury. [PDF]

Curr Pain Headache Rep, 2022
Johnson BN, McKernan LC, Bruehl S.
europepmc   +1 more source

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 172-185, January 2026.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

Molecular genetic basis of the primary emotions in young adults: an exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways. [PDF]

Front Pharmacol
Glavač T, Barbo M, Ravnik-Glavač M, Zupančič M, Dolžan V.   +4 more
europepmc   +1 more source

Stress-induced analgesia: an evaluation of effects on temporal summation of pain and the role of endogenous opioid mechanisms. [PDF]

Pain Rep, 2022
Bruehl S, Morris MC, al'Absi M.
europepmc   +1 more source

Pain-related effects of trait anger expression: Neural substrates and the role of endogenous opioid mechanisms

, 2008
Stephen Bruehl, John W. Burns, Ok Yung Chung, Melissa Chont   +3 more
openalex   +1 more source

Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review

BioFactors, Volume 52, Issue 1, January/February 2026.
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra, Chia‐Che Ku, Ying‐Chu Lin, Yi‐Chun Tsai, Deng‐Chyang Wu, Yukio Mitsui, Maki Satou, Yuuki Tanaka, Shigeo Saito, Kazunari K. Yokoyama   +9 more
wiley   +1 more source