Results 231 to 240 of about 74,218 (327)

Oral Melatonin in Critically Ill Patients With COVID‐19: A Quasi‐Experimental Pragmatic Trial

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Melatonin has demonstrated antioxidant, anti‐inflammatory, and potential antiviral properties. Its therapeutic role in critically ill COVID‐19 patients admitted to intensive care was underexplored at the start of the pandemic. We conducted a quasi‐experimental, pragmatic study over 4 consecutive uninterrupted time periods alternating control ...
Miguel Sánchez‐García, Jesús A.F. Tresguerres, Manuel Álvarez‐González, Belén de la Hera, Virginia Puebla, Lidia Ybañez, José‐Manuel Martínez‐Sesmero, Antonio Blesa, Juan‐Carlos Martín‐Benítez, Fernando Martínez‐Sagasti, Paloma González‐Arenas, Sara Domingo, Cándido Pardo, Silmary Maichle, Carolina Postigo, Sara De‐Miguel, María Bringas, Raquel González‐Casanova, Viktor Yordanov, Alberto Delgado‐Iribarren, Esther Culebras, Miguel A. Armengol‐de la‐Hoz, Antonio Núñez‐Reiz   +22 more
wiley   +1 more source

Single-neuron projectome-guided analysis reveals the neural circuit mechanism underlying endogenous opioid antinociception. [PDF]

Natl Sci Rev
Dou YN, Liu Y, Ding WQ, Li Q, Zhou H, Li L, Zhao MT, Li ZY, Yuan J, Wang XF, Zou WY, Li A, Sun YG.   +12 more
europepmc   +1 more source

Decision letter: Simultaneous brain, brainstem, and spinal cord pharmacological-fMRI reveals involvement of an endogenous opioid network in attentional analgesia

, 2021
Markus Ploner
openalex   +1 more source

G Protein‐Coupled Receptor Kinase 5 (GRK5) Modulates Nociceptin/Orphanin FQ Opioid (NOP) Receptor Desensitization in Rat Sympathetic Neurons

Journal of Neuroscience Research, Volume 104, Issue 1, January 2026.
ABSTRACT Stimulation of nociceptin/orphanin FQ peptide (NOP) opioid receptors by the endogenous ligand nociceptin (Noc) leads to voltage‐gated Ca2+ channel inhibition or G protein inwardly rectifying K+ channel activation. One mechanism of G protein‐coupled receptor (GPCR) desensitization occurs when G protein‐coupled receptor kinases (GRK ...
Mohamed Farrag, Marwa Soliman, Saifeldin Mahmoud, Lauren Miller, Paul B. Herold, Kristen Brandt, Victor Ruiz‐Velasco   +6 more
wiley   +1 more source

Endogenous Opioid Levels Do Not Correlate With Itch Intensity and Therapeutic Interventions in Hepatic Pruritus. [PDF]

Front Med (Lausanne), 2021
Düll MM, Wolf K, Vetter M, Dietrich P, Neurath MF, Kremer AE.   +5 more
europepmc   +1 more source

Postnatal maturation of endogenous opioid systems within the periaqueductal grey and spinal dorsal horn of the rat

, 2013
Charlie H.T. Kwok, Ian M. Devonshire, Andrew J. Bennett, Gareth J. Hathway   +3 more
openalex   +2 more sources

Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity

Lifestyle Medicine, Volume 7, Issue 1, January 2026.
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien, Sylvester Ifeanyi Omoruyi, Brendon Pearce, Melisse Erasmus, Nireshni Chellan   +4 more
wiley   +1 more source

Interactions Between Endocannabinoid and Endogenous Opioid Systems Prospectively Influence Postoperative Opioid Use in Pregnant Patients Undergoing Cesarean Delivery. [PDF]

J Pain
Stone AL, Pham A, Osmundson SS, Pedowitz A, Kingsley PJ, Marnett LJ, Patel S, Wickersham N, Sorabella LL, Bruehl S.   +9 more
europepmc   +1 more source

Modulation of luteinizing hormone and follicle-stimulating hormone in circulation by interactions between endogenous opioids and oestradiol during the peripubertal period of heifers [PDF]

, 1992
Michael W. Wolfe, Mark S. Roberson, T. T. Stumpf, R. J. Kittok, J. E. Kinder   +4 more
openalex   +1 more source

Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons

, 2021
Seksiri Arttamangkul, Emily J. Platt, James R. Carroll, David Farrens   +3 more
openalex   +1 more source