Results 251 to 260 of about 74,218 (327)
Neuro-physiological characterization of opioid peptide actions on neurohumoral transmission in the mammalian central nervous system [PDF]
, 1986 Mercuri, Nicola +4 more
core +1 more source
Economic Inquiry, Volume 64, Issue 1, Page 54-87, January 2026.Abstract In their 2022 study, ‘The Effects of Naloxone Access Laws on Opioid Abuse, Mortality, and Crime,’ Doleac and Mukherjee conclude that broadening access to a life‐saving drug—naloxone—does not reduce opioid‐related mortality as the drug simultaneously encourages riskier drug use. I show issues with their data, design, and estimation methods. For
Sergey Alexeev
wiley +1 more source
Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale
Geriatrics &Gerontology International, Volume 26, Issue 1, January 2026.ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi +4 more
wiley +1 more source
Journal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro +22 more
wiley +1 more source
Endogenous opioid peptides in the descending pain modulatory circuit. [PDF]
Neuropharmacology, 2020 Bagley EE, Ingram SL.
europepmc +1 more source
Journal of Neuroimaging, Volume 36, Issue 1, January/February 2026.ABSTRACT Background and Purpose Fibromyalgia (FM) is a chronic syndrome characterized by widespread musculoskeletal pain, hypersensitivity, and cognitive impairments. Alterations in brain functional connectivity have been suggested as possible mechanisms underlying pain amplification in these patients.
Gina Rodrigues de Oliveira +3 more
wiley +1 more source
Pain Research and Management, Volume 2026, Issue 1, 2026.Advanced cancer continues to pose a substantial global challenge, with complex symptom burdens and limited therapeutic options. Traditional Chinese Medicine (TCM), grounded in holistic theory and the principles of syndrome differentiation, employs interventions such as herbal medicine, acupuncture, moxibustion, and acupoint‐based therapies to address ...
Chunmeng Jiao +6 more
wiley +1 more source
Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue [PDF]
Filip Hanak +7 more
openalex +1 more source