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A Painful Endogenous Opioid
Science's STKE, 2006 Dynorphin A 1-17 is derived from proteolytic processing of prodynorphin and has high affinity for μ, δ, and κ opioid receptors. However, increased amounts of dynorphin A are found in models of chronic pain, and antibodies against dynorphin A alleviate, rather than potentiate, pain. Lai et al .openaire +1 more sourceOpioid Receptors and Endogenous Opioid Peptides
1980 According to Ariens et al. (1964b), the concept of receptors was first proposed by J. N. Langley in 1905 to account for the actions of nicotine and curare at the myoneural junction, and by P. Ehrlich in 1906 to account for specific interactions between antigens and antibodies and for the selectivity of dyes for certain components of living cells.openaire +1 more sourceEndogenous Opioid
2010 Bart Ellenbroek, Alfonso Abizaid, Shimon Amir, Martina de Zwaan, Sarah Parylak, Pietro Cottone, Eric P. Zorrilla, Lawrence H. Price, Ben J. Harrison, Christos Pantelis, Lawrence H. Price, Sophie Tambour, John C. Crabbe, Ian P. Stolerman, Nicola Simola, Micaela Morelli, Michael H. Bloch, Sarah Morgan, Angus Mackay, Gary Remington, Sidney H. Kennedy, Sakina J. Rizvi, Giovanni Hernandez, Peter Shizgal, Mitul A. Mehta, Ennio Esposito, Roberto William Invernizzi, Darren R. Christensen, Warren K. Bickel, Lynette C. Daws, Anne M. Andrews, Greg A. Gerhardt, Lawrence H. Price, Mischa de Rover, Sander Nieuwenhuis, Peter H. Boeijinga, Victoria L. Harvey, Anthony H. Dickenson, Peter Verheart, Per Svenningsson, Per E. Andrén, Antonio Pádua Carobrez, Grasielle C. Kincheski, Leandro J. Bertoglio, Kim Wolff, Iván Izquierdo, Lia Rejane M. Bevilaqua, Martin Cammarota, David H. Zald, Oliver Stiedl, Sven Ove Ögren, Joseph Zohar, Alan J. Budney, Oliver Stiedl, Sven Ove Ögren, Cecilia J. Hillard, Alfonso Abizaid, Shimon Amir, Josee E. Leysen, Samuel B. Hutton, Michael M. Morgan, MacDonald J. Christie, Paul Willner, Michael M. Morgan, MacDonald J. Christie, Martina de Zwaan, Jason C. G. Halford, Peter Riederer, Siegfried Hoyer, Francis C. Colpaert, Michael M. Morgan, MacDonald J. Christie, Michael M. Morgan, MacDonald J. Christie, Daniel Hoyer, Paul D. Callaghan, Iain S. McGregor, Murray R. Thompson, Kim Wolff, Mary E. Cain, Michael T. Bardo, Christoph Hiemke, Christoph Hiemke, Lawrence S. Wilkinson, Anthony R. Isles, Celia J. A. Morgan, Valerie H. Curran, Victoria L. Harvey, Anthony H. Dickenson, Mark Slifstein, Jos Prickaerts, David E. Nichols, Lawrence H. Price, Marc N. Branch, Mohammed Shoaib, Jill B. Becker, Marilyn E. Carroll, Peter A. Santi, Marilyn E. Carroll, Peter A. Santi, Juan J. López-Ibor, Maria-Inés López-Ibor, Maria-Inés López-Ibor, Juan J. López-Ibor, Berend Olivier, Naheed (Max) Mirza, Seiya Miyamoto, Mohammed Shoaib, Bernard Le Foll, Cyril Höschl, Sander Nieuwenhuis, Mischa de Rover, Mischa de Rover, Sander Nieuwenhuis, David S. Baldwin, Cyril Höschl, Thomas Steckler, Michel Billiard, Linda Lundström, Will Spooren, Silvia Gatti McArthur, Linda Lundström, Silvia Gatti McArthur, Will Spooren, Darrel J. Pemberton, Kim Wolff, Andrea Bari, Josee E. Leysen, Samuel B. Hutton, Amee B. Patel, Kim Fromme, Kim Fromme, Amee B. Patel, Kim Fromme, Amee B. Patel, Kim Fromme, Amee B. Patel, Suzanne H. Mitchell, Harriet de Wit, Matthew I. Palmatier, Rick A. Bevins, Victoria L. Harvey, Anthony H. Dickenson, David S. Tait, Verity J. Brown, W. Wolfgang Fleischhacker, Samuel B. Hutton +146 moreopenaire +1 more sourceEndogene Opioide (Endorphine, Enkephaline)
2002 Die endogenen Opioide haben aller Wahrscheinlichkeit nach eine entwicklungsgeschichtlich entscheidende Bedeutung beim Uberlebenskampf erlangt. Denn bei den unter einer Belastungssituation ausgelosten Reaktionen des protektiven Systems sind endogene Opioide in der Lage, diese zu blockieren, wenn sie zum Uberleben (Flucht oder Kampf) des Individuums nur ...openaire +1 more sourceOpioid Peptides, Endogenous
2012 Marleen A. Baak, Bernard Gutin, Kim A. Krawczewski Carhuatanta, Stephen C. Woods, Heinz W. Harbach, Megan M. Wenner, Nina S. Stachenfeld, Timothy M. Griffin, Romain Meeusen, Kevin Pauw, Axel Urhausen, Li Li Ji, David C. Poole, Steven W. Copp, Daniel M. Hirai, Timothy I. Musch +15 moreopenaire +2 more sources