Results 261 to 270 of about 603,777 (298)

Human endogenous retroviruses

BioEssays, 1988
AbstractSeveral studies have revealed the presence in human DNA of thousands of endogenous retrovirus genomes, or HERVs. Many HERVs are related to extant retroviruses that infect other vertebrates and some have been present in the germ line of primates for millions of years.
M, Cohen, E, Larsson
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Endogenous retroviruses and schizophrenia

Brain Research Reviews, 2000
Retroviruses are biologically complex infectious agents which are capable of cellular infection and subsequent integration into the host genome. Retroviruses can exist in an endogenous form in which viral sequences are integrated into the human germline and are vertically transmitted in a Mendelian fashion. The transcriptional activation of these viral
R H, Yolken, H, Karlsson, F, Yee, N L, Johnston-Wilson, E F, Torrey   +4 more
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Human Endogenous Retroviruses in Diseases

2023
Human endogenous retroviruses (HERVs), which are conserved sequences of ancient retroviruses, are widely distributed in the human genome. Although most HERVs have been rendered inactive by evolution, some have continued to exhibit important cytological functions.
Tian-Jiao, Fan, Jie, Cui
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Endogenous retroviruses and animal reproduction

Cytogenetic and Genome Research, 2005
Endogenous retroviruses (ERV), as part of the host genetic heritage, are transmissible to the next generation in a Mendelian way. Their abundance in animal genomes and their expression primarily detected in germ cells, embryonic tissues and cancer cell lines, raised the question of their biological significance.
S, Prudhomme, B, Bonnaud, F, Mallet
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Endogenous Retroviruses in Xenografts

New England Journal of Medicine, 1993
To the Editor: Pressed by the increasing shortage of human organs, we are rapidly moving toward the use of xenografts from pigs or nonhuman primates. We must ask whether endogenous animal retroviruses pose any public health risk when transplanted into a human host.
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Endogenous Human Retroviruses

1994
The genomes of all eukaryotes contain multiple copies of DNA sequences that are related to sequences found in infectious retroviruses (for review, see Coffin, 1984; Garfinkel, 1992). These elements are transmitted through the germ line as stable Mendelian genes, yet they exhibit structural and sequence similarities to infectious exogenous retroviruses.
David A. Wilkinson, Dixie L. Mager, Jo-Ann C. Leong   +2 more
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Human endogenous retroviruses and ADHD

The World Journal of Biological Psychiatry, 2013
Several lines of evidences suggest that human endogenous retroviruses (HERVs) are implicated in the development of many complex diseases with a multifactorial aetiology and a strong heritability, such as neurological and psychiatric diseases. Attention deficit hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that results from a complex ...
BALESTRIERI, EMANUELA, Pitzianti, M, MATTEUCCI, CLAUDIA, D'AGATI, ELISA, SORRENTINO, ROBERTA, Baratta, A, Caterina, R, ZENOBI, ROSSELLA, CURATOLO, PAOLO, GARACI, ENRICO, SINIBALDI VALLEBONA, PAOLA, PASINI, AUGUSTO   +11 more
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Xenotransplantation and pig endogenous retroviruses

Reviews in Medical Virology, 2003
AbstractXenotransplantation, in particular transplantation of pig cells, tissues and organs into human patients, may alleviate the current shortage of suitable allografts available for human transplantation. This overview addresses the physiological, immunological and virological factors considered with regard to xenotransplantation.
Saema, Magre, Yasuhiro, Takeuchi, Birke, Bartosch   +2 more
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Endogenous retroviruses and human disease

Expert Review of Clinical Immunology, 2006
Human endogenous retroviruses (HERVs) constitute up to 8% of the human genome. In general they are highly defective, but complete proviruses have also been described. Over time some transposable elements became inactive, while others retain mobility within the genome. Variably inserting in cellular genes, and differentially within the various allotypes
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Pig endogenous retroviruses and xenotransplantation

Xenotransplantation, 2002
Xenotransplantation of porcine organs might provide an unlimited source of donor organs to treat endstage organ failure diseases in humans. However, pigs harbour retroviruses with unknown pathogenic potential as an integral part of their genome. While until recently the risk of interspecies transmission of these porcine endogenous retroviruses (PERV ...
Jürgen H, Blusch, Clive, Patience, Ulrich, Martin   +2 more
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