Results 131 to 140 of about 2,262,534 (280)
Survey on deterministic endogenous security defense techniques for industrial Internet
To address the structural mismatch between strict operational constraints of the Industrial Internet and the conventional bolt-on, static-perimeter security paradigm, research on deterministic endogenous security defense was conducted.
Zhang Zhiwei +9 more
doaj
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng +8 more
wiley +1 more source
Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen +6 more
wiley +1 more source
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
The rapid development of wireless communications has put forward higher requirements for the design of security architectures for future communications.
LU Xinjin +4 more
doaj
Engineered Transformer Base Editor with Enhanced Editing Efficiency
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen +5 more
wiley +1 more source
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu +12 more
wiley +1 more source
Vanderbilt University Annual Security Report 2008
The Vanderbilt University Annual Security Report is published each year to provide information on security-related services offered by the ...
core
NEF-DHR: A Non-Equivalent Functional Dynamic Heterogeneous Redundancy Architecture for Endogenous Safety and Security. [PDF]
Jiang B, Kang Y, Cai H.
europepmc +1 more source
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou +4 more
wiley +1 more source

