Results 131 to 140 of about 132,565 (303)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Endogenous Timing in Pollution Control: Stackelberg versus Cournot-Nash Equilibria

open access: yes
In the framework of international cooperation on climate change to control greenhouse gas emissions (GHG), this paper aims to shed new light on the eventuality of the emergence of a country (or a group of countries) behaving as a leader in the ...
Melanie Heugues
core  

The Effects of Food on Circadian Rhythm: A Comprehensive Review

open access: yeseFood
Circadian rhythms regulate essential physiological functions such as metabolism, hormone secretion, and sleep–wake cycles. While light entrains the central clock in the suprachiasmatic nucleus (SCN), food serves as a powerful zeitgeber (an external ...
Jiazheng Hu   +7 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Endogenous business cycles and growth [PDF]

open access: yes
Current explanations why a growing economy necessarily goes through booms and recessions predict countercyclical R&D investment. As this is very controversial from an empirical perspective, a stochastic Poissonmodel of endogenous business cycles and ...
Wälde, Klaus
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Equilibrium Leadership in Tax Competition: The Role of Capital-Labor Substitution/Complement [PDF]

open access: yes
This paper examines endogenous leadership in tax competition using two countries with asymmetricity of population and three-input production functions, in which capital and labor are either complements or substitutes.
Tamai, Toshiki   +2 more
core  

Effects of juvenile hormone and ecdysone on the timing of vitellogenin appearance in hemolymph of queen and worker pupae of Apis mellifera

open access: yesJournal of Insect Science, 2002
The caste-specific regulation of vitellogenin synthesis in the honeybee represents a problem with many yet unresolved details. We carried out experiments to determine when levels of vitellogenin are first detected in hemolymph of female castes of Apis ...
Angel Roberto Barchuk   +2 more
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Endogenous Preemption on Both Sides of a Market

open access: yes
We study a market in which both buyers and sellers can decide to preempt and set their quantities before market clearing.Will this lead to preemption on both sides of the market, only one side of the market, or to no preemption at all?We find that ...
Güth, W., Potters, J.J.M., Müller, W.
core  

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