Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan +17 more
wiley +1 more source
The circadian clock gene CYCLE as a potential target for disrupting blood-feeding behavior in the mosquito Culex pipiens. [PDF]
Wijewardana C +11 more
europepmc +1 more source
Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO‐Chitosan Biointerfaces
Vapour phase metalation (VPM), multiplied pulsed vapour phase infiltration (MPI), and O2 plasma‑enhanced atomic layer deposition (PEALD) tailor Zn–chitosan (Zn‑CS) films. PEALD improves wettability and biocompatibility. MPI enhances semiconductor behavior. Antiseptic selectivity: VPM → E. coli; MPI → H. pylori.
Mabel Moreno +17 more
wiley +1 more source
Chronotherapeutic optimization of radioactive iodine therapy in differentiated thyroid cancer: The rationale for evening administration. [PDF]
Meristoudis G, Savvidis C, Ilias I.
europepmc +1 more source
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha +9 more
wiley +1 more source
Circadian Timing Moderates Diurnal Positive Affect Rhythms in Adolescents. [PDF]
Mirchandaney R +9 more
europepmc +1 more source
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou +9 more
wiley +1 more source
Direct or indirect: the crucial role of N-palmitate in hedgehog signaling. [PDF]
Puschmann J, Grobe K.
europepmc +1 more source
Natural Biomaterials for Osteochondral Repair: From Source to Strategy
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu +5 more
wiley +1 more source
Field assessment of melatonin timing reveals circadian misalignment beyond chronotype in elite female football players. [PDF]
Reis C +4 more
europepmc +1 more source

