Results 41 to 50 of about 122,555 (266)

Investment timing and quantity under ambiguity and business cycles

open access: yesJournal of Applied Economics
We extend a dynamic investment model that captures the conjoint effect of ambiguity and the business cycle on the investment threshold and endogenous investment quantity choice.
Wenhe Song, Shou Chen
doaj   +1 more source

The changes they are a-timed: Metabolism, endogenous clocks, and the timing of puberty.

open access: yesFrontiers in Endocrinology, 2012
Childhood obesity has increased dramatically over the last several decades, particularly in industrialized countries, often accompanied by acceleration of pubertal progression and associated reproductive abnormalities (Biro et al., 2006, Rosenfield et al.
Kristen P Tolson   +2 more
doaj   +1 more source

Individual variation in spawning migration timing in a salmonid fish—Exploring roles of environmental and social cues

open access: yesEcology and Evolution, 2023
Describing and explaining patterns of individual animal behaviors in situ, and their repeatability over the annual cycle, is an emerging field in ecology owing largely to advances in tagging technology.
Michio Fukushima, Peter S. Rand
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Regulation and Function of RFRP-3 (GnIH) neurons during postnatal development

open access: yesFrontiers in Endocrinology, 2015
RFamide-related peptide-3 (RFRP-3; mammalian ortholog to GnIH) potently inhibits gonadotropin secretion in mammals. Studies of RFRP-3 immunoreactivity and Rfrp expression (the gene encoding RFRP-3) in mammalian brains have uncovered several possible ...
Matthew C Poling, Alexander S. Kauffman
doaj   +1 more source

Local weather and endogenous factors affect the initiation of migration in short‐ and medium‐distance songbird migrants

open access: yesJournal of Avian Biology, 2023
Migratory birds employ a variety of mechanisms to ensure appropriate timing of migration based on integration of endogenous and exogenous information.
Theodore J. Zenzal   +3 more
doaj   +1 more source

Time Series Tests of Endogenous Growth Models [PDF]

open access: yesThe Quarterly Journal of Economics, 1995
Summary: According to endogenous growth theory, permanent changes in certain policy variables have permanent effects on the rate of economic growth. Empirically, however, U.S. growth rates exhibit no large persistent changes. Therefore, the determinants of long-run growth highlighted by a specific growth model must similarly exhibit no large persistent
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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