A fatty acid-rich fraction of an endolichenic fungus Phoma sp. suppresses immune checkpoint markers via AhR/ARNT and ESR1 [PDF]
Lung cancer has the highest mortality rates worldwide. The disease is caused by environmental pollutants, smoking, and many other factors. Recent treatments include immunotherapeutics, which have shown some success; however, the search for new ...
Mücahit Varlı +11 more
doaj +2 more sources
Four novel endolichenic fungi from Usnea spp. (Lecanorales, Parmeliaceae) in Yunnan and Guizhou, China: Taxonomic description and preliminary assessment of bioactive potentials [PDF]
Usnea is one of the largest and most diverse genera of fruticose lichens with global distribution. Endolichenic fungi, which thrive within lichen thalli, have emerged as a promising source of bioactive compounds, with the ability to synthesise a variety ...
Runlei Chang +6 more
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Molecular phylogeny and bioprospecting of Endolichenic Fungi (ELF) inhabiting in the lichens collected from a mangrove ecosystem in Sri Lanka. [PDF]
Endolichenic fungi (ELF) are unexplored group of organisms as a source for the production of bioactive secondary metabolites with radical scavenging activity, antilipase and amylase inhibitory activities.
Kasun Maduranga +4 more
doaj +2 more sources
Biodiscovery of antibacterial constituents from the endolichenic fungi isolated from Parmotrema rampoddense. [PDF]
A total of nine endolichenic fungi were isolated from the foliose lichen Parmotrema rampoddense (Nyl.) Hale. Of the nine endolichenic fungi, three taxa (Fusarium proliferatum, Nemania primolutea, Daldinia eschsholtzii) showed antibacterial activities as determined by the disk diffusion assay against ESKAPE bacterial pathogens.
Tan MA +6 more
europepmc +4 more sources
The complete mitochondrial genome sequence of Trichoderma texanum (Hypocreales, Sordariomycetes) [PDF]
Trichoderma texanum is a species of saprotrophic and endolichenic fungus in the genus Trichoderma. In this study, we sequenced and analyzed the complete mitochondrial genome of T. texanum strain CSC21B0438. The mitochondrial genome of T.
Munkhgerel Dalantai, Seung-Yoon Oh
doaj +2 more sources
Exploring the influence of climatic variables on mycobiome composition and community diversity in lichens: insights from structural equation modeling analysis [PDF]
Background Lichens are symbiotic organisms composed of a fungus and a photosynthetic partner, which are key ecological bioindicators due to their sensitivity to environmental changes.
Jiho Yang +4 more
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Endolichenic Fungal Community Analysis by Pure Culture Isolation and Metabarcoding: A Case Study of Parmotrema tinctorum [PDF]
Lichen is a symbiotic mutualism of mycobiont and photobiont that harbors diverse organisms including endolichenic fungi (ELF). Despite the taxonomic and ecological significance of ELF, no comparative investigation of an ELF community involving isolation ...
Ji Ho Yang +3 more
doaj +2 more sources
Genomic-Driven Identification of Conserved Biosynthetic Gene Clusters in Cladosporium limoniforme: The Case of the DHN-Melanin Pathway [PDF]
Background: Endolichenic fungi represent an emerging source of bioactive secondary metabolites; however, the genomic basis of their chemical diversity remains largely poorly characterized.
Angela Rojas-Coll +3 more
doaj +2 more sources
1′-O-methyl-averantin isolated from the endolichenic fungus Jackrogersella sp. EL001672 suppresses colorectal cancer stemness via sonic Hedgehog and Notch signaling [PDF]
Endolichenic fungi are host organisms that live on lichens and produce a wide variety of secondary metabolites. Colorectal cancer stem cells are capable of self-renewal and differentiation into cancer cells, which makes cancers difficult to eradicate ...
Mücahit Varlı +10 more
doaj +2 more sources
An acetonic extract and secondary metabolites from the endolichenic fungus Nemania sp. EL006872 exhibit immune checkpoint inhibitory activity in lung cancer cell [PDF]
Background: Endolichenic fungi (ELF), which live the inside the lichen thallus, contain many secondary metabolites that show various biological activities.
Mücahit Varlı +11 more
doaj +2 more sources

