Results 91 to 100 of about 24,031 (238)

Electrocochleography for Ménière's disease: is it reliable?,

Brazilian Journal of Otorhinolaryngology, 2014
Introduction: Endolymphatic hydrops, the histopathological substrate of Ménière's disease, is an almost universal finding in postmortem studies of patients with this disease.
Pauliana Lamounier, Débora Aparecida Gobbo, Thiago Silva Almeida de Souza, Carlos Augusto Costa Pires de Oliveira, Fayez Bahmad Jr.   +4 more
doaj   +1 more source

Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 89-100, February 2026.
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Min‐Fei Qian, Hao Chen, Qi‐Xuan Wang, Ya‐Qi Zhou, Xiao‐Lu Chen, Zhi‐Wu Huang, Ji‐Ping Li   +6 more
wiley   +1 more source

MR imaging of endolymphatic hydrops in Ménière’s disease: feasibility at 1.5 T

The Egyptian Journal of Radiology and Nuclear Medicine
Background Ménière’s disease is a chronic condition of the inner ear that causes vertigo, tinnitus and hearing loss. Its diagnosis relies on clinical criteria that are subjective and pure-tone audiometry results that are not specific.
Amine Ben Lakhal, Seif Boukriba, Rim Bechraoui, Sondes Mannoubi, Habiba Mizouni   +4 more
doaj   +1 more source

Vestibular Migraine‐Like Syndrome in a Patient With Postttraumatic Headache and Medication‐Overuse Headache

Case Reports in Otolaryngology, Volume 2026, Issue 1, 2026.
Vestibular migraine (VM) requires a migraine history according to ICHD‐3, but recurrent vertigo may also develop in secondary headache disorders. We report a 52‐year‐old man who experienced persistent headache and recurrent vertigo following a traffic accident.
Fumiyuki Goto, Takanobu Teramura, Shoji Kaneda, Kenji Okami, Koichiro Wasano, Kenichi Takano   +5 more
wiley   +1 more source

A Novel LMX1A Frameshift Variant Underlies Familial Phenotypic Heterogeneity in DFNA7

Human Mutation, Volume 2026, Issue 1, 2026.
Pathogenic variants in the LIM‐homeodomain transcription factor LMX1A represent a rare yet critical etiology for autosomal dominant nonsyndromic hearing loss 7 (DFNA7) and less frequently, its autosomal recessive counterpart (ARNSHL). Here, we describe a novel heterozygous frameshift variant, LMX1A c.405delT (p.Phe135LeufsTer3), identified in a three ...
Chenyang Xu, Zhipeng Nie, Suyang Wang, Yiming Zhu, Xiaowen Liu, Yufen Guo, Stuart Scott   +6 more
wiley   +1 more source

Otopathologic Patterns of Cellular Degeneration in the Peripheral Vestibular Organ Secondary to Head Trauma

The Laryngoscope, Volume 135, Issue 10, Page 3859-3866, October 2025.
This study examines vestibular degeneration following head trauma, comparing cases with and without fractures. Histopathological analysis of 26 temporal bones showed more severe damage in nonfracture cases, particularly in Scarpa's ganglion cells and vestibular hair cells.
Tomotaka Shimura, Mio Takeuchi, Nevra Keskin Yilmaz, Dilshan Rajan, Sebahattin Cureoglu, Sei Kobayashi, Rafael da Costa Monsanto   +6 more
wiley   +1 more source

Modulation of hearing function following the downgrading or upgrading of endolymphatic hydrops in Meniere's disease patients with endolymphatic duct blockage.

PLoS ONE, 2020
The present study was to investigate the dynamics of endolymphatic hydrops (EH) and hearing function, and explore whether the hearing loss is caused by EH alone and whether the hearing function can be modulated by changes in the EH.
Anquan Peng, Junjiao Hu, Qin Wang, Wenqi Jiang, Wei Liu, Zhiwen Zhang, Chao Huang, Yichao Chen   +7 more
doaj   +1 more source

Blood Labyrinth Barrier Waste Clearance as Assessed by GBCAs on MRI: A Scoping Review

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.
ABSTRACT Objective The discovery of the glymphatic system in the brain and eye has raised the hypothesis of a similar system in the inner ear. Dysfunctional lymph fluid dynamics may contribute to inner ear conditions such as Meniere's Disease (MD) and endolymphatic hydrops (EH).
Syed Ameen Ahmad, Emily Y. Huang, Joon Soo Kim, Yassine Balhi, Marcus Spann, Bryan K. Ward   +5 more
wiley   +1 more source

Delayed Effect of Active Pressure Treatment on Endolymphatic Hydrops [PDF]

, 2017
OBJECTIVE: To identify eventual correlations between the effect of low-pressure treatment and endolymphatic hydrops in Ménière patients. MATERIAL AND METHODS: The study group consisted of subjects affected by definite Ménière disease (2015) and a ...
Vania Marrone, Chiara Filippi, BENINCASA, ANNA TERESA, Tarentini, S., Edoardo Covelli, Luigi Volpini, Simonetta Monini, COVELLI, EDOARDO, FILIPPI, CHIARA, Silvia Tarentini, VOLPINI, LUIGI, ATTURO, FRANCESCA, VESTRI, Anna Rita, Maurizio Barbara, Annarita Vestri, Francesca Atturo, Marrone, V., BARBARA, Maurizio, MONINI, Simonetta, Anna Teresa Benincasa   +19 more
core   +2 more sources

Different Contribution of Missense and Loss‐of‐Function Variants to the Genetic Structure of Familial and Sporadic Meniere Disease

MedComm, Volume 6, Issue 10, October 2025.
This study examines the genetic basis of sporadic (SMD) and familial Meniere disease (FMD) by comparing rare protein‐coding variants using exome sequencing and gene burden analysis. FMD patients had a higher accumulation of missense and LoF variants, especially in genes linked to auditory and vestibular function.
Alberto M. Parra‐Perez, Alvaro Gallego‐Martinez, Alba Escalera‐Balsera, Paula Robles‐Bolivar, Patricia Perez‐Carpena, Jose A. Lopez‐Escamez   +5 more
wiley   +1 more source