Results 41 to 50 of about 2,587 (173)
Objective: Endolymphatic sac surgery is effective in treating intractable Meniere's disease (MD), but the underlying mechanism is still unknown. Our study investigated the mechanism by which endolymphatic sac-mastoid shunt (EMS) surgery is effective in ...
Yawei Li +10 more
doaj +1 more source
Intervention Outcomes for Meniere's Disease: An Umbrella Review
ABSTRACT Objective To assess and summarize the outcomes of major pharmacologic, device‐based, and surgical interventions reported in systematic reviews and meta‐analyses for the treatment of Meniere's disease. Data Sources CINAHL, Cochrane, PubMed, Scopus.
Warren B. Chun +7 more
wiley +1 more source
Effects of Glucocorticoids on the Inner Ear
Hypothesis: Recently, several lines of evidence have suggested that the inner ear is under hormonal control. It is likely that steroids have some influence on the inner ear.Background: Many clinicians have been empirically using steroids for the ...
Taizo Takeda +2 more
doaj +1 more source
Audiological Characteristics in Vestibular Schwannoma Patients
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng +4 more
wiley +1 more source
Contralateral delayed endolymphatic hydrops: Clinical features and long term outcome
Background: Contralateral delayed endolymphatic hydrops (CDEH) is a clinical entity characterized by fluctuating low frequency hearing loss and/or vertigo, mimicking Ménière’s disease (MD), that manifests after the appearance of severe non-hydropic ...
Andrea Albera +5 more
doaj +1 more source
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
[Delayed endolymphatic hydrops].
Delayed Endolymphatic Hydrops (DEH) is a disease entity that must be distinguished from idiopathic endolymphatic hydrops (Ménière's disease). Idiopathic hydrops is characterized by the following symptoms: 1) vertigo often accompanied by nausea and vomiting; 2) tinnitus; 3) hearing loss, usually fluctuating; and 4) sensation of pressure or fullness in ...
GIANNONI, BEATRICE +2 more
openaire +3 more sources
Progress On Sensorineural Hearing Loss: Mechanisms and Therapies
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang +9 more
wiley +1 more source
Safety of acute exposure to the food additive glycerol (E 422) from beverages
Abstract The European Commission requested EFSA to assess the acute exposure to glycerol (E 422) from slush ice drinks and de‐alcoholised wine. The acute exposure assessment was conducted on a single‑consumption‑event basis considering the reported use levels and analytical data of glycerol in slush ice drinks and the proposed maximum level of 50,000 ...
EFSA Panel on Food Additives and Flavourings (FAF) +22 more
wiley +1 more source

