Results 51 to 60 of about 2,499 (175)

Electrocochleography for Ménière's disease: is it reliable?,

Brazilian Journal of Otorhinolaryngology, 2014
Introduction: Endolymphatic hydrops, the histopathological substrate of Ménière's disease, is an almost universal finding in postmortem studies of patients with this disease.
Pauliana Lamounier, Débora Aparecida Gobbo, Thiago Silva Almeida de Souza, Carlos Augusto Costa Pires de Oliveira, Fayez Bahmad Jr.   +4 more
doaj   +1 more source

A Synchrotron and Micro-CT Study of the Human Endolymphatic Duct System: Is Meniere's Disease Caused by an Acute Endolymph Backflow?

Frontiers in Surgery, 2021
Background: The etiology of Meniere's disease (MD) and endolymphatic hydrops believed to underlie its symptoms remain unknown. One reason may be the exceptional complexity of the human inner ear, its vulnerability, and surrounding hard bone.
Hao Li, Gunesh P. Rajan, Gunesh P. Rajan, Jeremy Shaw, Seyed Alireza Rohani, Hanif M. Ladak, Sumit Agrawal, Helge Rask-Andersen   +7 more
doaj   +1 more source

Blood Labyrinth Barrier Waste Clearance as Assessed by GBCAs on MRI: A Scoping Review

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.
ABSTRACT Objective The discovery of the glymphatic system in the brain and eye has raised the hypothesis of a similar system in the inner ear. Dysfunctional lymph fluid dynamics may contribute to inner ear conditions such as Meniere's Disease (MD) and endolymphatic hydrops (EH).
Syed Ameen Ahmad, Emily Y. Huang, Joon Soo Kim, Yassine Balhi, Marcus Spann, Bryan K. Ward   +5 more
wiley   +1 more source

Endolymphatic Hydrops and Blockage of the Endolymphatic Duct [PDF]

Otology & Neurotology, 2009
Endolymphatic hydrops, or dilation of the endolymphatic space, was first described independently in 1938 by Yamakawa (1) and Hallpike and Cairns (2) as the foremost pathologic correlate to Meniere's disease. Guild (3) had described the movement of endolymph toward the endolymphatic sac, noting that endolymph is formed by the stria vascularis, flows ...
Fred H, Linthicum, Aron M, Gortman
openaire   +2 more sources

Different Contribution of Missense and Loss‐of‐Function Variants to the Genetic Structure of Familial and Sporadic Meniere Disease

MedComm, Volume 6, Issue 10, October 2025.
This study examines the genetic basis of sporadic (SMD) and familial Meniere disease (FMD) by comparing rare protein‐coding variants using exome sequencing and gene burden analysis. FMD patients had a higher accumulation of missense and LoF variants, especially in genes linked to auditory and vestibular function.
Alberto M. Parra‐Perez, Alvaro Gallego‐Martinez, Alba Escalera‐Balsera, Paula Robles‐Bolivar, Patricia Perez‐Carpena, Jose A. Lopez‐Escamez   +5 more
wiley   +1 more source

Limited Utility of Existing Hearing Loss Panels in the Assessment of Early‐Onset, Bilateral Meniere's Disease

OTO Open, Volume 9, Issue 4, October-December 2025.
Abstract Objective While the etiology of Meniere's disease (MD) is likely multifactorial, genetics are thought to play a role. Several previous studies have yielded inconclusive results, potentially due to phenotypic uncertainty and variable diagnostic criteria.
Keshav V. Shah, Christian Jung, Daniel Talian, Sherrie Davis, Douglas J. Epstein, Michael J. Ruckenstein, Tiffany P. Hwa   +6 more
wiley   +1 more source

MR imaging of endolymphatic hydrops in Ménière’s disease: feasibility at 1.5 T

The Egyptian Journal of Radiology and Nuclear Medicine
Background Ménière’s disease is a chronic condition of the inner ear that causes vertigo, tinnitus and hearing loss. Its diagnosis relies on clinical criteria that are subjective and pure-tone audiometry results that are not specific.
Amine Ben Lakhal, Seif Boukriba, Rim Bechraoui, Sondes Mannoubi, Habiba Mizouni   +4 more
doaj   +1 more source

Modulation of hearing function following the downgrading or upgrading of endolymphatic hydrops in Meniere's disease patients with endolymphatic duct blockage.

PLoS ONE, 2020
The present study was to investigate the dynamics of endolymphatic hydrops (EH) and hearing function, and explore whether the hearing loss is caused by EH alone and whether the hearing function can be modulated by changes in the EH.
Anquan Peng, Junjiao Hu, Qin Wang, Wenqi Jiang, Wei Liu, Zhiwen Zhang, Chao Huang, Yichao Chen   +7 more
doaj   +1 more source

Intracochlear Imaging Using IVUS and OFDI: A Cadaveric Feasibility Study

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 4, August 2025.
This study evaluates the feasibility of optical frequency domain imaging (OFDI) and intravascular ultrasound (IVUS) for intracochlear imaging in human cadaveric specimens. OFDI provided high‐resolution visualization of cochlear microstructures, while IVUS enabled deeper penetration and broader coverage.
Ayu Akazawa, Takeshi Fujita, Jun Yokoi, Natsumi Uehara, Mie Kubo, Akinobu Kakigi, Ken‐ichi Nibu   +6 more
wiley   +1 more source

Severe self‐limiting acute bilateral hearing loss following a low dose of methylphenidate for ADHD treatment: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Atefeh Zandifar, Rahim Badrfam
wiley   +1 more source