Results 71 to 80 of about 5,907 (233)

Different Contribution of Missense and Loss‐of‐Function Variants to the Genetic Structure of Familial and Sporadic Meniere Disease

MedComm, Volume 6, Issue 10, October 2025.
This study examines the genetic basis of sporadic (SMD) and familial Meniere disease (FMD) by comparing rare protein‐coding variants using exome sequencing and gene burden analysis. FMD patients had a higher accumulation of missense and LoF variants, especially in genes linked to auditory and vestibular function.
Alberto M. Parra‐Perez, Alvaro Gallego‐Martinez, Alba Escalera‐Balsera, Paula Robles‐Bolivar, Patricia Perez‐Carpena, Jose A. Lopez‐Escamez   +5 more
wiley   +1 more source

Comorbid symptoms occurring during acute low-tone hearing loss (AHLH) as potential predictors of Meniere's disease [PDF]

, 2018
Acute low-tone sensorineural hearing loss (ALHL) is a type of idiopathic sudden sensorineural hearing loss. ALHL is rarely a solitary condition but rather co-occurs with vertigo and tinnitus, being an element of contemporary diagnostic criteria for ...
Droste, Judith, Olze, Heidi, Stölzel, Katharina, Szczepek, Agnieszka J., Voß, Linda Josephine   +4 more
core   +2 more sources

Limited Utility of Existing Hearing Loss Panels in the Assessment of Early‐Onset, Bilateral Meniere's Disease

OTO Open, Volume 9, Issue 4, October-December 2025.
Abstract Objective While the etiology of Meniere's disease (MD) is likely multifactorial, genetics are thought to play a role. Several previous studies have yielded inconclusive results, potentially due to phenotypic uncertainty and variable diagnostic criteria.
Keshav V. Shah, Christian Jung, Daniel Talian, Sherrie Davis, Douglas J. Epstein, Michael J. Ruckenstein, Tiffany P. Hwa   +6 more
wiley   +1 more source

Hydropic Ear Disease: Correlation Between Audiovestibular Symptoms, Endolymphatic Hydrops and Blood-Labyrinth Barrier Impairment

Frontiers in Surgery, 2021
Research Objective: To investigate the correlation between clinical features and MRI-confirmed endolymphatic hydrops (EH) and blood-labyrinth barrier (BLB) impairment.Study Design: Retrospective cross-sectional study.Setting: Vertigo referral center ...
Lisa M. H. de Pont, Lisa M. H. de Pont, Josephine M. van Steekelenburg, Thijs O. Verhagen, Thijs O. Verhagen, Thijs O. Verhagen, Maartje Houben, Maartje Houben, Jelle J. Goeman, Berit M. Verbist, Mark A. van Buchem, Claire C. Bommeljé, Henk M. Blom, Henk M. Blom, Henk M. Blom, Sebastiaan Hammer   +15 more
doaj   +1 more source

Predicting positive cochlear endolymphatic hydrops on magnetic resonance images [PDF]

, 2022
Kao‐Tsung Lin, Chi‐Ju Lu, Yi‐Ho Young   +2 more
openalex   +1 more source

[Delayed endolymphatic hydrops].

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 1998
Delayed Endolymphatic Hydrops (DEH) is a disease entity that must be distinguished from idiopathic endolymphatic hydrops (Ménière's disease). Idiopathic hydrops is characterized by the following symptoms: 1) vertigo often accompanied by nausea and vomiting; 2) tinnitus; 3) hearing loss, usually fluctuating; and 4) sensation of pressure or fullness in ...
GIANNONI, BEATRICE, PAGNINI, PAOLO, VANNUCCHI, PAOLO   +2 more
openaire   +3 more sources

A Synchrotron and Micro-CT Study of the Human Endolymphatic Duct System: Is Meniere's Disease Caused by an Acute Endolymph Backflow?

Frontiers in Surgery, 2021
Background: The etiology of Meniere's disease (MD) and endolymphatic hydrops believed to underlie its symptoms remain unknown. One reason may be the exceptional complexity of the human inner ear, its vulnerability, and surrounding hard bone.
Hao Li, Gunesh P. Rajan, Gunesh P. Rajan, Jeremy Shaw, Seyed Alireza Rohani, Hanif M. Ladak, Sumit Agrawal, Helge Rask-Andersen   +7 more
doaj   +1 more source

On the role of depletive tests. a review analysis [PDF]

, 2016
An overview of the diagnostic role of depletion tests for staging Meniere’s disease, especially in the first phase of the disease, is reported.
Barbara, M, Covelli, E, Marrone, V, Monini, S, Tarentini, S   +4 more
core  

Intratympanic corticosteroids in Ménière's disease: A mini-review [PDF]

, 2017
This article reviews the effectiveness of intratympanic corticosteroids for vertigo control in Ménière's disease at 2-years follow-up according to the guidelines expressed by the American Academy of Otolaryngology-Head & Neck Surgery.
AAO-HNS, Albu, Albu, Atrache Al Attrache, Barrs, Bird, Boleas-Aguirre, Brookes, Casani, Dodson, Doyle, Espinosa-Sanchez, Frejo, Frejo, Fukushima, Gabra, Garduño-Anaya, Gazquez, Greco, Hamid, Herraiz, Hirvonen, Itoh, James, Kayan, Lavigne, Lee, Leng, Liu, Martin Sanz, Martin-Sanz, McCabe, McRackan, Miller, Minor, Moffat, Paragache, Parnes, Patel, Phillips, Pondugula, Pullens, Pullens, Rauch, Rauch, Ren, Riente, Sajjadi, Sakata, Salt, Sennaroğlu, She, Shea, Shin, Shirwany, Silverstein, Silverstein, Suzuki, Söderman, Thirlwall, Trune, Trune, van Sonsbeek, Wick, Wladislavosky-Waserman, Xenellis   +65 more
core   +2 more sources

Intracochlear Imaging Using IVUS and OFDI: A Cadaveric Feasibility Study

Laryngoscope Investigative Otolaryngology, Volume 10, Issue 4, August 2025.
This study evaluates the feasibility of optical frequency domain imaging (OFDI) and intravascular ultrasound (IVUS) for intracochlear imaging in human cadaveric specimens. OFDI provided high‐resolution visualization of cochlear microstructures, while IVUS enabled deeper penetration and broader coverage.
Ayu Akazawa, Takeshi Fujita, Jun Yokoi, Natsumi Uehara, Mie Kubo, Akinobu Kakigi, Ken‐ichi Nibu   +6 more
wiley   +1 more source