Results 11 to 20 of about 133,448 (228)
AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency [PDF]
Molecular Therapy: Methods & Clinical Development, 2022 Inner ear gene therapy using adeno-associated viruses (AAVs) has been successfully applied to several mouse models of hereditary hearing loss to improve their auditory function. While most inner ear gene therapy studies have focused on the mechanosensory
Kevin Isgrig +8 more
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Frontiers in Neurology, 2019 Meniere's disease is a common disease, that presents with recurrent vertigo and cochlear symptoms. The pathology of Meniere's disease was first reported to involve endolymphatic hydrops in 1938. The endolymphatic sac is thought to have a role to keep the
Taeko Ito +9 more
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Imaging Analysis of Patients With Meniere's Disease Treated With Endolymphatic Sac-Mastoid Shunt Surgery [PDF]
Frontiers in Surgery, 2022 Objective: Endolymphatic sac surgery is effective in treating intractable Meniere's disease (MD), but the underlying mechanism is still unknown. Our study investigated the mechanism by which endolymphatic sac-mastoid shunt (EMS) surgery is effective in ...
Yawei Li +10 more
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Histopathology of the Endolymphatic Sac
Practica Oto-Rhino-Laryngologica, 1980 胎児15例, 小児・成人69例の合計153耳における内リンパ嚢の組織学的特徴を調べた. 胎児内リンパ嚢は広い腔と平坦な上皮を特徴としていた. 成人では中間部から樹枝型に分岐してしまう型があり, 内腔の狭小が予想された. 嚢周囲の色素はおそらくメラニンであり, 病的所見ではないように思われたが, 成人耳の44%に存在した. 内腔にポリープ様突出物があるのも19%にみられたが, その病的意義は不明である. 嚢内沈着物は47%の例に高度に貯溜されており, 内容は酸性ムコ多糖・中性ムコ多糖・ムコ蛋白などの物質であることがわかった.
Tetsuo Ishii, Sachiko Moriguchi
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Radiology Case Reports, 2011 Endolymphatic sac tumor is an uncommon, locally aggressive tumor. The tumor is located in the medial and posterior petrosal bone region and may involve the dura. A hypervascular tumor involving the endolymphatic sac with destructive changes, it involves the bone and may show reactive new bone formation. Diagnosis is based on clinical, radiological, and
Raghu H. Ramakrishnaiah +4 more
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Cytology of Endolymphatic Sac Tumor [PDF]
Modern Pathology, 2001 A 77-year-old man presented with decreased mental status and an enhancing partially cystic tumor along the left tentorium on magnetic resonance imaging after mastoidectomy and petrosectomy for an "auditory canal tumor." Smears of the aspirated cyst fluid revealed rare epithelial cell clusters, some with papillary features, foamy macrophages, and blood.
Kim R. Geisinger +2 more
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Triple semicircular canal occlusion with endolymphatic sac decompression for intractable Meniere’s disease [PDF]
Frontiers in NeurologyBackgroundMeniere’s disease (MD) is characterized by idiopathic endolymphatic hydrops (ELH). Frequent vertigo attacks is the most disabling symptom of MD.ObjectiveThis study evaluated the efficacy of triple semicircular canal occlusion combined with ...
Jiawang Tian +5 more
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Philippine Journal of Otolaryngology Head and Neck Surgery, 2009 We present the case of a 48 year old lady with a history of episodic hearing loss and tinnitus of several years duration. One month prior to consult, there was note of left occipital pain.
Jose M. Carnate, Amado O. Tandoc
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New marsupialization technique in endolymphatic sac surgery [PDF]
Laryngoscope Investigative Otolaryngology, 2020 Objectives The aim of the present study was to describe and evaluate the results of a new technique in endolymphatic sac decompression surgery. Methods Forty‐three patients with intractable unilateral Meniere's disease were selected.
Ahmad Daneshi +5 more
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Vestibular Aqueduct Morphology Correlates With Endolymphatic Sac Pathologies in Menière's Disease-A Correlative Histology and Computed Tomography Study. [PDF]
Otol Neurotol, 2019 Hypothesis: The vestibular aqueduct (VA) in Menière's disease (MD) exhibits different angular trajectories depending on the presenting endolymphatic sac (ES) pathology, i.e., 1) ES hypoplasia or 2) ES degeneration.
Bächinger D +10 more
europepmc +2 more sources