Results 41 to 50 of about 2,796 (172)

Audiological Characteristics in Vestibular Schwannoma Patients

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Vestibular schwannoma (VS) is a benign tumor that originates from the Schwann cells of the vestibular nerve sheath in the internal auditory canal. This retrospective study collected data from patients with VS who underwent surgical treatment to identify their demographic characteristics and audiometric features.
Shan Zeng, Yi‐Yun Lou, Hui‐Qian Yu, Wei‐Dong Zhao, Wen‐Yan Li   +4 more
wiley   +1 more source

Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter? [PDF]

PLoS ONE, 2018
INTRODUCTION:Middle ear application of gentamicin is a common medical treatment for uncontrolled Ménière's disease. The objective of the study was to evaluate the impact of endolymphatic hydrops on inner ear delivery.
Pedro Marques, Maoli Duan, Nicolas Perez-Fernandez, Jorge Spratley   +3 more
doaj   +1 more source

The tympanic covering layer contributes to basilar membrane elasticity potentially influencing human frequency resolution and speech perception

Journal of Anatomy, Volume 249, Issue 3, Page 528-543, September 2026.
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu, Claudia Steinacher, Alexander Glueckert, Rudolf Glueckert, Hao Li, Karin Staxäng, Anneliese Schrott‐Fischer, Hanif M. Ladak, Sumit Agrawal, Helge Rask‐Andersen   +9 more
wiley   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

Head &Neck, Volume 48, Issue 8, Page 2271-2280, August 2026.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue, Yang Zhao, Huiying Sun, Hanlin Chen, Yong Zhao, Xin Ding, Wanru Zheng, Fei Ren, Yiwei Zhao, Jiajing Tong, Yu Chen, Zhiqiang Gao, Xu Tian, Siyi Cai, Guodong Feng   +14 more
wiley   +1 more source

SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice.

PLoS Genetics, 2013
Mutations of SLC26A4 are a common cause of human hearing loss associated with enlargement of the vestibular aqueduct. SLC26A4 encodes pendrin, an anion exchanger expressed in a variety of epithelial cells in the cochlea, the vestibular labyrinth and the ...
Xiangming Li, Joel D Sanneman, Donald G Harbidge, Fei Zhou, Fei Zhou, Taku Ito, Raoul Nelson, Nicolas Picard, Régine Chambrey, Dominique Eladari, Tracy Miesner, Andrew J Griffith, Daniel C Marcus, Philine Wangemann   +13 more
doaj   +1 more source

Large endolymphatic sac anomaly [PDF]

Pediatric Radiology, 2010
A 31-month-old girl presented with sensorineural hearing loss. Brain MRI demonstrated enlargement of the endolymphatic sacs bilaterally on T2-W images (Fig. 1) and reformatted image on the left side (Fig. 2, white arrow). The remaining inner ear structures were unremarkable. The endolymphatic sac sits at the posterior aspect of the petrous bone.
Karl, Muchantef, Ajay, Malhotra
openaire   +2 more sources

Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance

The Laryngoscope, Volume 136, Issue 8, Page 3559-3568, August 2026.
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi, Sylvain Bourdoncle, Jean Fanet, Stéphane Gargula, Denis Ayache, Loïc Duron, Julien Savatovsky, Guillaume Poillon   +7 more
wiley   +1 more source

Results of surgical treatment of patients with Meniere’s disease

Медицинский совет, 2019
The study analyzed the clinical effect of the surgical treatment of 25 patients with Meniere’s disease, 20 of which underwent endolymphatic sac drainage and five of which underwent vestibular neurectomy via translabyrinthine approach.
V. M. Svistushkin, S. V. Morozova, E. G. Varosyan, I. T. Mukhamedov, D. B. Bidanova   +4 more
doaj   +1 more source

What a Neurosurgeon Should Know About the Endolymphatic Sac: Part 3 – Ménière Disease

Brazilian Neurosurgery, 2023
Objective To elucidate all the aspects that neurosurgeons should know about the Ménière disease (MD). Methods Review of guidelines, books, and studies from 1933 to 2021, from basic to translational research, using human and animal ...
Marco Antônio Schlindwein Vaz, Jander Moreira Monteiro, Joel Lavinsky, Giuseppe Casella Santis, Marcelo Assis Moro da Rocha Filho, Carmen Austrália Paredes Marcondes Ribas, Ricardo Marques Lopes de Araújo, Eberval Gadelha Figueiredo, Gustavo Rassier Isolan   +8 more
doaj   +1 more source

Diagnostic Challenges in Choroid Plexus Tumours

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
In this review, we summarise the diagnostic spectrum of choroid plexus tumours, highlight key age‐dependent differential diagnoses across infants, children/adolescents and adults, and outline how histopathology, immunohistochemistry and molecular profiling support accurate tumour classification.
Christian Thomas, Martin Hasselblatt
wiley   +1 more source