Results 1 to 10 of about 445,400 (301)

Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids [PDF]

open access: yesStem Cell Reports, 2019
Summary: Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Pei-Ciao Tang   +8 more
doaj   +3 more sources

Refining surgical techniques for efficient posterior semicircular canal gene delivery in the adult mammalian inner ear with minimal hearing loss

open access: yesScientific Reports, 2021
Hearing loss is a common disability affecting the world’s population today. While several studies have shown that inner ear gene therapy can be successfully applied to mouse models of hereditary hearing loss to improve hearing, most of these studies rely
Jianliang Zhu   +6 more
doaj   +1 more source

Fzd3 Expression Within Inner Ear Afferent Neurons Is Necessary for Central Pathfinding

open access: yesFrontiers in Neuroscience, 2022
During development the afferent neurons of the inner ear make precise wiring decisions in the hindbrain reflective of their topographic distribution in the periphery.
Zachary A. Stoner   +6 more
doaj   +1 more source

Inner ear malformation

open access: yesListy klinicke logopedie, 2020
Inner ear malformation comprises a broad group of disorders, the main symptom of which is hearing loss. The disorder occurs during the embryonic development of the auditory system. Only about 20 % of malformations can be diagnosed radiologically. Hearing
Dagmar Hošnová, Milan Urík
doaj   +1 more source

Nanocarriers for Inner Ear Disease Therapy

open access: yesFrontiers in Cellular Neuroscience, 2021
Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects.
Xiaoxiang Xu   +10 more
doaj   +1 more source

The Role of FoxG1 in the Inner Ear

open access: yesFrontiers in Cell and Developmental Biology, 2020
Sensorineural deafness is mainly caused by damage to the tissues of the inner ear, and hearing impairment has become an increasingly serious global health problem.
Yanyan Ding   +7 more
doaj   +1 more source

Mouse Embryonic Fibroblasts-Derived Extracellular Matrix Facilitates Expansion of Inner Ear-Derived Cells [PDF]

open access: yesCell Journal, 2023
Objective: Previous reports showed that mouse embryonic fibroblasts (MEFs) could support pluripotent stem cell selfrenewaland maintain their pluripotency.
Junming Zhang   +4 more
doaj   +1 more source

Molecular and functional characterization of gap junctions in the avian inner ear. [PDF]

open access: yes, 2006
To analyze the fundamental role of gap junctions in the vertebrate inner ear, we examined molecular and functional characteristics of gap junctional communication (GJC) in the auditory and vestibular system of the chicken.
Becker, D, Forge, A, Nickel, R
core   +1 more source

Biomarkers for Inner Ear Disorders: Scoping Review on the Role of Biomarkers in Hearing and Balance Disorders

open access: yesDiagnostics, 2020
The diagnostics of inner ear diseases are primarily functional, but there is a growing interest in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature regarding the definition, classification system, and an overview
Nahla A. Gomaa   +4 more
doaj   +1 more source

Inner ear morphology in the Atlantic molly Poecilia mexicana [PDF]

open access: yes, 2011
Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Hess, Martin   +2 more
core   +1 more source

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