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Current strategies for drug delivery to the inner ear
Acta Pharmaceutica Sinica B, 2013 For many years, drug delivery to the inner ear has been a challenge to physicians in the treatment of inner ear disorders. In the past decade, the field of inner ear drug delivery has emerged with the development of new biomaterials and drug delivery ...
Hongzhuo Liu, Jinsong Hao, S Kevin Li
exaly +3 more sources
Scientific Reports, 2021 Hearing loss is a common disability affecting the world’s population today. While several studies have shown that inner ear gene therapy can be successfully applied to mouse models of hereditary hearing loss to improve hearing, most of these studies rely
Jianliang Zhu +6 more
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Fzd3 Expression Within Inner Ear Afferent Neurons Is Necessary for Central Pathfinding
Frontiers in Neuroscience, 2022 During development the afferent neurons of the inner ear make precise wiring decisions in the hindbrain reflective of their topographic distribution in the periphery.
Zachary A. Stoner +6 more
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Nanocarriers for Inner Ear Disease Therapy
Frontiers in Cellular Neuroscience, 2021 Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects.
Xiaoxiang Xu +10 more
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Listy klinicke logopedie, 2020 Inner ear malformation comprises a broad group of disorders, the main symptom of which is hearing loss. The disorder occurs during the embryonic development of the auditory system. Only about 20 % of malformations can be diagnosed radiologically. Hearing
Dagmar Hošnová, Milan Urík
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The Role of FoxG1 in the Inner Ear
Frontiers in Cell and Developmental Biology, 2020 Sensorineural deafness is mainly caused by damage to the tissues of the inner ear, and hearing impairment has become an increasingly serious global health problem.
Yanyan Ding +7 more
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The inner ear and the neurologist [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2007 Inner ear disorders are common and patients with vestibular failure often present to a neurology clinic because of their dizziness, gait unsteadiness and oscillopsia. Vestibular disorders can be divided into peripheral and central vestibular disorders.
Charlotte, Agrup +2 more
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Proteomics and the Inner Ear [PDF]
Disease Markers, 2001 The inner ear, one of the most complex organs, contains within its bony shell three sensory systems, the evolutionary oldest gravity receptor system, the three semicircular canals for the detection of angular acceleration, and the auditory system ‐ unrivaled in sensitivity and frequency discrimination.
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Mouse Embryonic Fibroblasts-Derived Extracellular Matrix Facilitates Expansion of Inner Ear-Derived Cells [PDF]
Cell Journal, 2023 Objective: Previous reports showed that mouse embryonic fibroblasts (MEFs) could support pluripotent stem cell selfrenewaland maintain their pluripotency.
Junming Zhang +4 more
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Diagnostics, 2020 The diagnostics of inner ear diseases are primarily functional, but there is a growing interest in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature regarding the definition, classification system, and an overview
Nahla A. Gomaa +4 more
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