Results 11 to 20 of about 1,367,224 (352)
The Bulletin of Tokyo Medical and Dental University, 1985 Inner ear barotrauma was observed by compressing or decompressing guinea pigs. The barotrauma in compression was greatly influenced by auditory tube function, and, in the animals deprived of this function, we could observe far more severe damage of inner ear hair cells and far more frequent round window rupture than in animals not thus deprived ...
Shigeki, TAKAHASHI
openaire +4 more sources
Progenitor Cells from the Adult Human Inner Ear [PDF]
The Anatomical Record, 2019 Loss of inner ear hair cells leads to incurable balance and hearing disorders because these sensory cells do not effectively regenerate in humans. A potential starting point for therapy would be the stimulation of quiescent progenitor cells within the ...
P. Senn +5 more
semanticscholar +3 more sources
Inner Ear Disorders in SCUBA Divers: A Review [PDF]
, 2021 Self-Contained Underwater Breathing Apparatus (SCUBA) diving is a popular sport. However, improper diving may injure different organs. The majority of dive-related disorders concern otolaryngology, and may include hearing loss, tinnitus, aural fullness ...
Matteo Cavaliere +15 more
core +1 more source
Nanocarriers for Inner Ear Disease Therapy
Frontiers in Cellular Neuroscience, 2021 Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects.
Xiaoxiang Xu +10 more
doaj +1 more source
Journal of Neuroscience, 2020 Age-related hearing loss arises from irreversible damage in the inner ear, where sound is transduced into electrical signals. Prior human studies suggested that sensory-cell loss is rarely the cause; correspondingly, animal work has implicated the stria ...
Pei-zhe Wu +3 more
semanticscholar +1 more source
Genetic Causes of Sensorineural Hearing Loss Associated with Inner Ear Malformations [PDF]
, 2022 Clinically significant hearing loss is present in ~1 per 500 newborns and affects more than 30% of the population at some time in their lives. Empowered by the astounding progress in DNA sequencing technology, recent studies have brought the number of ...
Tekin, Mustafa +3 more
core +1 more source
Exosomes mediate sensory hair cell protection in the inner ear.
Journal of Clinical Investigation, 2020 Hair cells are the mechanosensory receptors of the inner ear, responsible for hearing and balance. Hair cell death and consequent hearing loss are common results of treatment with ototoxic drugs, including the widely-used aminoglycoside antibiotics ...
Andrew M. Breglio +12 more
semanticscholar +1 more source
The Mechanosensory Transduction Machinery in Inner Ear Hair Cells
Annual Review of Biophysics, 2020 Sound-induced mechanical stimuli are detected by elaborate mechanosensory transduction (MT) machinery in highly specialized hair cells of the inner ear.
Wang Zheng, J. Holt
semanticscholar +1 more source
Drug Delivery across Barriers to the Middle and Inner Ear
Advanced Functional Materials, 2020 The prevalence of ear disorders has spurred efforts to develop drug delivery systems to treat these conditions. Here, recent advances in drug delivery systems that access the ear through the tympanic membrane (TM) are reviewed.
Zipei Zhang +3 more
semanticscholar +1 more source
Drug Delivery Device for the Inner Ear: Ultra-sharp Fully Metallic Microneedles
Drug Delivery and Translational Research, 2020 Drug delivery into the inner ear is a significant challenge due to its inaccessibility as a fluid-filled cavity within the temporal bone of the skull. The round window membrane (RWM) is the only delivery portal from the middle ear to the inner ear that ...
Aykut Aksit +6 more
semanticscholar +1 more source