Results 31 to 40 of about 96,350 (311)

Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice. [PDF]

, 2013
BACKGROUND: Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is caused by a 1.5-3 Mb microdeletion of chromosome 22q11.2, frequently referred to as 22q11.2 deletion syndrome (22q11DS).
Morrow BE, Nowotschin, Sonja, Pirity MK, Baldini, Antonio, Freyer L, Freyer, Laina, Nowotschin S, Pirity, Melinda K., Morrow, Bernice E.   +8 more
core   +1 more source

Inner ear morphology in the Atlantic molly Poecilia mexicana - first detailed microanatomical study of the inner ear of a cyprinodontiform species

, 2011
Background: Fishes show an amazing diversity in hearing abilities, inner ear structures, and otolith morphology. Inner ear morphology, however, has not yet been investigated in detail in any member of the diverse order Cyprinodontiformes.
Heß, Martin, Plath, Martin, Tanja Schulz-Mirbach, Martin Hess, Schulz-Mirbach, Tanja, Schulz-Mirbach Tanja, Plath Martin, Martin Plath, Heß Martin   +8 more
core   +1 more source

Precision medicine: a new era for inner ear diseases

Frontiers in Pharmacology
The inner ear is the organ responsible for hearing and balance. Inner ear dysfunction can be the result of infection, trauma, ototoxic drugs, genetic mutation or predisposition. Often, like for Ménière disease, the cause is unknown.
Elisa Tavazzani, Elisa Tavazzani, Paolo Spaiardi, Paolo Spaiardi, Donatella Contini, Giulio Sancini, Giulio Sancini, Giancarlo Russo, Sergio Masetto   +8 more
doaj   +1 more source

Genetic Causes of Inner Ear Anomalies: a Review from the Turkish Study Group for Inner Ear Anomalies

Balkan Medical Journal, 2019
Inner ear anomalies diagnosed using a radiological study are detected in almost 30% of cases with congenital or prelingual-onset sensorineural hearing loss.
Emre Ocak, Duygu Duman, Mustafa Tekin
doaj   +1 more source

Otitis media impacts hundreds of mouse middle and inner ear genes. [PDF]

PLoS ONE, 2013
Otitis media is known to alter expression of cytokine and other genes in the mouse middle ear and inner ear. However, whole mouse genome studies of gene expression in otitis media have not previously been undertaken.
Carol J MacArthur, Fran Hausman, J Beth Kempton, Dongseok Choi, Dennis R Trune   +4 more
doaj   +1 more source

Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.

, 2015
The Notch signaling pathway controls differentiation of hair cells and supporting cells in the vertebrate inner ear. Here, we have investigated whether Numb, a known regulator of Notch activity in Drosophila, is involved in this process in the embryonic ...
Mark eEddison, Weber, SJ, Ariza-McNaughton, L, Julian eLewis, Nicolas eDaudet, Lewis, J, Sara Johanna Weber, Eddison, M, Daudet, N, Linda eAriza-McNaughton   +9 more
core   +1 more source

Macrophage-related immune responses in inner ear: a potential therapeutic target for sensorineural hearing loss

Frontiers in Neuroscience
Hearing loss is the most common sensory disorder in human beings. Cochlear sensory cells are the basis of hearing. Cochlear sensory cells suffer from various acute or chronic injuries, such as excessive sound stimulation, ototoxic drugs, and age-related ...
Yu-Chen Liu, Kai Xu
doaj   +1 more source

Generation of Vestibular Tissue-Like Organoids From Human Pluripotent Stem Cells Using the Rotary Cell Culture System

Frontiers in Cell and Developmental Biology, 2019
Hair cells are specialized mechanosensitive cells responsible for mediating balance and hearing within the inner ear. In mammals, hair cells are limited in number and do not regenerate.
Cristiana Mattei, Cristiana Mattei, Rebecca Lim, Hannah Drury, Babak Nasr, Babak Nasr, Babak Nasr, Zihui Li, Melissa A. Tadros, Giovanna M. D'Abaco, Kathryn S. Stok, Bryony A. Nayagam, Mirella Dottori, Mirella Dottori, Mirella Dottori   +14 more
doaj   +1 more source

Extratympanic Observation of Middle and Inner Ear Structures in Rodents Using Optical Coherence Tomography [PDF]

Clinical and Experimental Otorhinolaryngology, 2020
Objectives This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic ...
Se-Joon Oh, Il-Woo Lee, Soo-Geun Wang, Soo-Keun Kong, Hong-Ki Kim, Eui-Kyung Goh   +5 more
doaj   +1 more source

Immune system of the inner ear as a novel therapeutic target for sensorineural hearing loss

Frontiers in Pharmacology, 2014
Sensorineural hearing loss (SNHL) is a common clinical condition resulting from dysfunction in one or more parts in the auditory pathway between the inner ear and auditory cortex.
Takayuki eOkano
doaj   +1 more source