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Meniere's disease is a common disease, that presents with recurrent vertigo and cochlear symptoms. The pathology of Meniere's disease was first reported to involve endolymphatic hydrops in 1938. The endolymphatic sac is thought to have a role to keep the
Taeko Ito +9 more
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Background: Loudness recruitment is commonly experienced by patients with putative endolymphatic hydrops. Loudness recruitment is abnormal loudness growth with high-level sounds being perceived as having normal loudness even though hearing thresholds are
Shannon M. Lefler +5 more
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Current Treatment of Endolymphatic Sac Tumor of the Temporal Bone. [PDF]
Mendenhall WM +8 more
europepmc +3 more sources
Endolymphatic sac tumor: rewiev of literature
Endolymphatic sac tumors are rare neoplasms of the temporal bone, histologically benign, but clinically behaves as malignant tumors causing destruction of surrounding tissues.
Kh.M.A. Diab +6 more
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“Endolymphatic sac tumour”: A case report with review of literature
Endolymphatic sac tumour (ELST) is a non-metastasizing low grade adenocarcinoma of endolymphatic sac origin. It is also known as Heffner tumour, low grade adenocarcinoma of endolymphatic sac origin and aggressive papillary middle ear tumour.
B Rajeshwari +4 more
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Endolymphatic sac surgery [PDF]
AbstractThere is a disturbing variation in the reported success rate in Endolymphatic Sac Surgery in the literature. Relatively long‐term (24 months to 10 years) follow‐ups are given in a series of 66 patients in this paper. Results reveal only a 55% long‐term relief of veitigo in these patients.
openaire +3 more sources
Molecular architecture underlying fluid absorption by the developing inner ear
Mutations of SLC26A4 are a common cause of hearing loss associated with enlargement of the endolymphatic sac (EES). Slc26a4 expression in the developing mouse endolymphatic sac is required for acquisition of normal inner ear structure and function. Here,
Keiji Honda +11 more
doaj +1 more source
Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. [PDF]
Loss-of-function mutations of SLC26A4/pendrin are among the most prevalent causes of deafness. Deafness and vestibular dysfunction in the corresponding mouse model, Slc26a4(-/-), are associated with an enlargement and acidification of the membranous ...
Hyoung-Mi Kim, Philine Wangemann
doaj +1 more source
BackgroundPostauricular injection as a local therapy has been confirmed to be effective for inner ear diseases. However, the mechanism for the drugs entering the inner ears remains unknown.
Aiping Chen +7 more
doaj +1 more source
Visualization and clinical relevance of the endolymphatic duct and sac in Ménière's disease
BackgroundMénière's disease (MD) is a chronic inner ear disorder with a multifactorial etiology. Decreased visualization of the endolymphatic duct (ED) and sac (ES) is thought to be associated with MD, although controversy exists about whether this ...
Lisa M. H. de Pont +12 more
doaj +1 more source

