p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer-relevant paralog interplay. [PDF]
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Pinault M +12 more
europepmc +2 more sources
Ambulatory diagnosis of endometrial pathology [PDF]
The aim of this thesis was to determine the diagnostic accuracy of outpatient endometrial evaluation using endometrial biopsy (EB), ultrasound scan (USS) and hysteroscopy (OPH) by conducting systematic quantitative reviews of the published literature ...
Clark, Thomas Justin
core +7 more sources
Caracterització del factor de transcripció ERM/ETV5 durant la infiltració miometrial i aproximacions proteòmiques al procés d'invasió en càncer d'endometri [PDF]
[cat] El càncer d'endometri és la malaltia ginecològica més comuna i representa la quarta neoplàsia més freqüent en la dona en els països desenvolupats.
Monge i Azemar, Marta
core +6 more sources
Outcomes of Proton Beam Therapy Compared With Intensity-Modulated Radiation Therapy for Uterine Cancer [PDF]
Purpose: To compare Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) in patients with endometrial cancer receiving adjuvant pelvic radiation therapy with proton beam therapy (PT) versus intensity ...
Justin D. Anderson, MD +9 more
doaj +1 more source
Lactobacillus-Loaded Bioadhesive Hydrogel with Prolonged Retention and Microenvironmental Remodeling for Endometrial Repair and Fertility Restoration. [PDF]
A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Chen L +9 more
europepmc +2 more sources
BackgroundThe Mayo criteria are the most widely accepted algorithm for predicting the risk of lymph node metastasis in endometrial endometrioid carcinoma (EEC).
Wen Lu +6 more
doaj +1 more source
Endometrial Hyperplasia and Endometrial Carcinoma [PDF]
Endometrial hyperplasia and endometrial carcinoma are rare in young women, but the incidence is continually increasing in developed countries due to obesity and metabolic diseases.
Wimberger, Pauline +5 more
core +1 more source
Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa +13 more
core +1 more source
Mutations and amplification of oncogenes in endometrial cancer [PDF]
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
Niederacher, Dieter +5 more
core +1 more source
Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair
Endometrial injury is the main fact leading to infertility. Current treatments of endometrial injury present many problems, such as unable to achieve desired effects due to low retention and the inherent potential risk of injury. Besides, it is important
Rong Dong +7 more
doaj +1 more source

