Expert consensus on genetic counseling in gynecological oncology (2023 edition) [PDF]
With the increasing applications of high-throughput genome sequencing technology, there is a growing recognition of the important roles of genetic factors in the occurrence and development of gynecological tumors.
doaj +1 more source
Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding : systematic review and meta-analysis of data from individual patients [PDF]
Peer reviewedPublisher ...
J. P. Daniels +10 more
core +2 more sources
Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome. [PDF]
The contraceptive effectiveness of intrauterine devices (IUDs) has been attributed in part to a foreign body reaction in the endometrium. We performed this study to better understand mechanisms of action of contraceptives of by studying their effects on ...
Averbach, Sarah +6 more
core
VIP contribution to the decidualization program: regulatory T cell recruitment [PDF]
During early pregnancy, the human uterus undergoes profound tissue remodeling characterized by leukocyte invasion and production of proinflammatory cytokines, followed by tissue repair and tolerance maintenance induction.
Agüero, Mariana +5 more
core +1 more source
Mismatch Repair Universal Screening of Endometrial Cancers (MUSE) in a Canadian Cohort
Background: Approximately 2–6% of endometrial cancers (ECs) are due to Lynch Syndrome (LS), a cancer predisposition syndrome caused by germline pathogenic variants (PVs) affecting the DNA mismatch repair (MMR) pathway.
Jessica Lawrence +7 more
doaj +1 more source
Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal +46 more
core +1 more source
Population-level cancer incidence rates are one measure to estimate the cancer burden. The goal is to provide information on trends to measure progress against cancer at the population level and identify emerging patterns signifying increased risk for ...
Sarah eTemkin +2 more
doaj +1 more source
Objective To compare the safety and efficacy of single end-point coagulator versus T-shaped sliding coagulator used for tactile electrosurgical endometrial ablation (TEEA) in stopping or decreasing active resistant perimenopausal intrauterine ball (IUB).
Mahmoud A Badawy
doaj +1 more source
Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa +6 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source

