Results 101 to 110 of about 333,113 (197)

Endometrial stromal cells of women with recurrent miscarriage fail to discriminate between high- and low-quality human embryos [PDF]

, 2012
Background The aetiology of recurrent miscarriage (RM) remains largely unexplained. Women with RM have a shorter time to pregnancy interval than normally fertile women, which may be due to more frequent implantation of non-viable embryos.
Weimar, Charlotte H. E., Gellersen, Birgit, Heijnen Cobi J., Johanna M T de Vreeden-Elbertse, Jan J. Brosens (109247), de Vreeden-Elbertse Johanna M. T., de Vreeden-Elbertse, Johanna M.T., Nick S Macklon, Macklon Nick S., Kavelaars, Annemieke, Charlotte H. E. Weimar (148304), Nick S. Macklon (148320), Jan J Brosens, Weimar Charlotte H. E., Gellersen Birgit, Cobi J. Heijnen (148314), Brosens Jan J., Macklon, Nick S., Weimar, Charlotte H.E., Kavelaars Annemieke, Cobi J Heijnen, Charlotte H E Weimar, Birgit Gellersen (148307), de Vreeden-Elbertse, Johanna M. T., Brosens, Jan J., Heijnen, Cobi J., Annemieke Kavelaars, Annemieke Kavelaars (12570), Birgit Gellersen, Johanna M. T. de Vreeden-Elbertse (148309)   +29 more
core   +2 more sources

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

Cancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal, Laura Spinelli, Nisha Kriplani, Helen Wise, Nadege Poncet, Giulia Marzano, Karen E. Anderson, Katarzyna M. Grzes, Zofia Varyova, Mahreen Adil, C. Peter Downes, Phillip T. Hawkins, Len R. Stephens, Kate G. Storey, Doreen A. Cantrell, Bart Vanhaesebroeck, Nicholas R. Leslie   +16 more
wiley   +1 more source

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

Primary Nodal Poroid Hidradenocarcinoma With YAP1::NUTM1 Fusion: Report of a Rare Case

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Poroid hidradenocarcinoma is a rare malignant sweat gland neoplasm. Although primary nodal hidradenoma has been reported, primary nodal poroid hidradenocarcinoma has not been described. We report a case of a 56‐year‐old man presenting with a nontender 5.5 cm mass within the axillary lymph node, and no identifiable primary cutaneous lesion on ...
Niloufar Hosseini, Omar Sbeanaty, William J. Phillips, Bryan Lo, Sandeep Sehdev, Thomas Brenn   +5 more
wiley   +1 more source

Endometrial pattern in women with abnormal uterine bleeding attending a tertiary care centre of Kathmandu

Journal of Pathology of Nepal
Background: Abnormal uterine bleeding is one of the most common problems among pre and postmenopausal women. Abnormal uterine bleeding is diagnosed when there is a substantial change in frequency, duration, or amountof bleeding during or between ...
Deliya Paudel, Himanshu Regmi
doaj   +1 more source

Clinical Outcomes of Gradual Corticosteroid Tapering for Immune Checkpoint Inhibitor‐Induced Liver Injury

Hepatology Research, EarlyView.
Patients with severe ICI‐induced liver injury are commonly treated with corticosteroids, but the optimal tapering strategy remains uncertain. In this study, a gradual corticosteroid tapering strategy based partly on Japanese clinical practice for autoimmune hepatitis was associated with a low rate of relapse and enabled many patients to safely resume ...
Naoto Soma, Yoshihito Uchida, Kayoko Sugawara, Masamitsu Nakao, Nobuaki Nakayama, Yukinori Imai, Suguru Mizuno, Satoshi Mochida   +7 more
wiley   +1 more source

Fertility-Sparing Treatment of Endometrial Cancer: Survey of Australian Practice. [PDF]

Aust N Z J Obstet Gynaecol
ABSTRACT Background Endometrial cancer is the most common gynaecological malignancy in Australia. Patients diagnosed in their reproductive window may desire a fertility‐sparing approach, opposed to standard surgical care. International guidelines on fertility‐sparing management exist; however, these highlight the lack of high‐level evidence to support ...
Odgers H, Farrell R.
europepmc   +2 more sources

Hippo pathway disruption and YAP1 activation in anogenital papillary squamous intraepithelial lesion

Histopathology, EarlyView.
Disruption of the Hippo Pathway with YAP1 activation is a consistent finding in papillary squamous intraepithelial lesions and may underlie their altered epithelial maturation and HPV E6/E7 expression patterns, providing new insight into the pathogenesis of this distinct low‐risk HPV‐associated lesion.
Gloria Zhang, Karen L. Talia, W. Glenn McCluggage, Robert A. Soslow, Bin Yang   +4 more
wiley   +1 more source

Estudo comparativo entre a ultra-sonografia transvaginal e a vídeo-histeroscopia diagnóstica na avaliação da cavidade uterina. [PDF]

, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Amboni Filho, Iveraldo
core  

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source