Results 1 to 10 of about 92,378 (163)

Concurrent Endometrial Carcinoma in Patients with a Curettage Diagnosis of Endometrial Hyperplasia

Journal of the Formosan Medical Association, 2009
Endometrial hyperplasia is considered a precursor of endometrial carcinoma, but concurrent endometrial carcinoma in patients with endometrial hyperplasia is seen frequently.
Yu-Li Chen, Wen-Fang Cheng, Ming-Chieh Lin, Chia-Yen Huang, Chang-Yao Hsieh, Chi-An Chen   +5 more
doaj   +3 more sources

Proteogenomic Characterization of Endometrial Carcinoma [PDF]

Cell, 2020
We undertook a comprehensive proteogenomic characterization of 95 prospectively collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This analysis revealed possible new consequences of perturbations to the p53 and Wnt/β-catenin pathways, identified a potential role for circRNAs in the epithelial-mesenchymal transition, and
Christopher R Kinsinger, Ana I Robles, David Fenyö   +2 more
exaly   +5 more sources

Undifferentiated endometrial carcinoma: a case report [PDF]

Journal of Medical Case Reports
Background Undifferentiated endometrial carcinoma is a solid tumor that originates from endometrial epithelial cells, accounting for approximately 9% of endometrial cancers.
Zhongyi Gu, Qingtao Tang, Shenglian Lu
doaj   +2 more sources

Study of ER, PR and VEGF Expression in Endometrial Epithelial Neoplasms and its Association with Histological Stage and Grade of Endometrial Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Exogenous or endogenous oestrogen induces hyperplastic endometrium which presents with abnormal uterine bleeding. Atypical endometrial hyperplasia is the precursor for endometrial carcinoma. In case of invasive carcinoma, oestrogen Receptor
SK Samim Rahaman, Rathin Hazra, Nirmalya Chakrabarti, Prasenjit Kumar Bar   +3 more
doaj   +1 more source

OCT4, Ki-67 and VEGF as Prognostic Factors in Endometrial Carcinoma and Their Role in The Differentiation between Atypical Endometrial Hyperplasia and Grade 1 Endometrial Carcinoma: an Immunohistochemical study [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
Background: Endometrial carcinoma develops through preliminary stages of endometrial hyperplasia. A population of epithelial stem cells was identified in the human endometrium, these cells may serve as a source of putative endometrial carcinoma. The most
Noha El-Anwar, Alaa Amer
doaj   +1 more source

lncRNA-ZFAS1 promotes the progression of endometrial carcinoma by targeting miR-34b to regulate VEGFA expression

Open Medicine, 2021
Zinc finger nuclear transcription factor, X-box binding 1-type containing 1 antisense RNA 1 (ZFAS1) functions as an oncogenic long noncoding RNA (lncRNA) to promote proliferation and metastasis of endometrial carcinoma cell; however, the underlying ...
Zhu Hongli, Cheng Qihui, Cai Hong
doaj   +1 more source

A first-in-class POLRMT specific inhibitor IMT1 suppresses endometrial carcinoma cell growth

Cell Death and Disease, 2023
Exploring novel molecularly-targeted therapies for endometrial carcinoma is important. The current study explored the potential anti-endometrial carcinoma activity by a first-in-class POLRMT (RNA polymerase mitochondrial) inhibitor IMT1.
Shu-ping Li, Li Ou, Yan Zhang, Fang-rong Shen, You-guo Chen   +4 more
doaj   +1 more source

The Expression and Clinical Significance of Sphingosine Kinase 1 and Vascular Endothelial Growth Factor in Endometrial Carcinoma

Emergency Medicine International, 2022
The aim of the study is to investigate the expression of sphingosine kinase 1 (SPHK1) and vascular endothelial growth factor (VEGF) in patients with endometrial carcinoma and its clinical significance. The tissues of 86 cases of patients with endometrial
Hong Yu, null Dejizhuoga, Wei Huang, Donglian Wang, null Gamaquzhen, Xiaomin Jia, Hao Feng   +6 more
doaj   +1 more source

Postablation Endometrial Carcinoma [PDF]

JSLS : Journal of the Society of Laparoendoscopic Surgeons, 2017
Many women have undergone both resectoscopic and nonresectoscopic (or global) endometrial ablation (EA) during the past 20 years. These women are now approaching their sixth and seventh decades of life, a time frame in which endometrial carcinoma (EC) is most frequently diagnosed.In several reports, surgeons have expressed concern that endometrial ...
Wortman, Morris, Vilos, George A., Vilos, Angelos G., Abu-Rafea, Basim, Dwyer, Wendy, Spitz, Robert   +5 more
openaire   +4 more sources

Livin/BIRC7 gene expression as a possible diagnostic biomarker for endometrial hyperplasia and carcinoma

Journal of Genetic Engineering and Biotechnology, 2021
Background Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family which are implicated in development of cancer through the inhibition of apoptosis process.
Basma K. Elmekkawy, Rasha M. S. Shoaib, Amal K. Seleem, Dalia Shalaan, Entsar A. Saad   +4 more
doaj   +1 more source