Results 151 to 160 of about 934,404 (297)

An update on pacemaking in the myometrium

The Journal of Physiology, EarlyView.
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley   +1 more source

A critical structured review of economic evaluations of interventions for the prevention and treatment of osteoporosis [PDF]

Osteoporosis is a major cause of morbidity, mortality and resource cost amongst the elderly population. Hip fracture is the most serious of the osteoporotic fractures, with approximately 10-20% of patients dying within six months of sustaining a fracture.
Bernie O'Brien, David Torgerson, Mark Sculpher, Ron Goeree   +3 more
core  

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Manual vacuum aspiration (women's MVA) for endometrial biopsy for patients with suspected endometrial malignancies. [PDF]

J Obstet Gynaecol Res, 2022
Saito E, Matsumoto Y, Nitta S, Fujino S, Tsuruga T, Mori-Uchino M, Iwase H, Kasamatsu T, Kugu K, Osuga Y.   +9 more
europepmc   +1 more source

Office Hysteroscopy and Pipelle Endometrial Biopsy versus Diltation and Curettage in Diagnosis of Endometrial pathology in women with perimenopausal bleeding. [PDF]

, 2019
Ahmed Magdy Lotfy Abdelmageed, Ahmed I. Abdo, tarek el beheidy, ashraf Nasr Refaie   +3 more
openalex   +1 more source

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

Diagnostic Cytopathology, Volume 54, Issue 3, Page 197-205, March 2026.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma, Xiaofei Yu, Xiaohong Duan, Siqian Huang, Sishi Bai, Baizhou Li   +5 more
wiley   +1 more source

Endometrial Cancer Arising in Adenomyosis That Could Not Be Diagnosed by Endometrial Biopsy: A Case Report. [PDF]

Yonago Acta Med, 2022
Chikumi J, Oishi T, Nakaso T, Sawada M, Kudoh A, Komatsu H, Sato S, Taniguchi F, Harada T.   +8 more
europepmc   +1 more source

Blinded Assessment of Serial Endometrial Biopsies and Cytology Following Intrauterine Misoprostol in the Mare

, 2023
Candace Lyman, Peyton Draheim, Christopher Premanandan, Stuart C. Clark‐Price, Robyn R. Wilborn   +4 more
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

If treating obesity with GLP‐1‐based therapies protects the heart, could it also prevent cancer or improve cancer outcomes? The case for randomized trials

Diabetes, Obesity and Metabolism, EarlyView.
Anastasios Tentolouris, Ioannis Ntanasis‐Stathopoulos   +1 more
wiley   +1 more source