Results 111 to 120 of about 210,312 (353)

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Sensor technologies in cancer research for new directions in diagnosis and treatment: and exploratory analysis [PDF]

open access: yesarXiv, 2022
The goal of this study is an exploratory analysis concerning main sensor technologies applied in cancer research to detect new directions in diagnosis and treatments. The study focused on types of cancer having a high incidence and mortality worldwide: breast, lung, colorectal and prostate.
arxiv  

Progesterone receptors in development and metatstais of endometrial cancer [PDF]

open access: yes, 2004
Many women may acquire endometrial cancer during their life. The vast majority of these women will be cured because of early detection of the disease. As in most types of cancer however, the main cause of death lies in metastasis of the primary tumor ...
Hanekamp, E.E. (Eline)
core   +1 more source

Total tissue lactate dehydrogenase activity in endometrial carcinoma [PDF]

open access: yes, 2008
Lactate dehydrogenase (LDH) is essential for continuous glycolysis necessary for accelerated tumor growth. The aim of this study was to reconsider if assay of total tissue activity of this enzyme could be useful as marker for endometrial carcinoma (EC ...
Abramić, Marija   +4 more
core   +1 more source

Performance of Liquid Biopsy‐Based Multi‐Omics Biomarkers for Early Detection of Gynecological Malignancies: A Prospective Study (PERCEIVE‐I)

open access: yesAdvanced Science, EarlyView.
Following a comparative analysis of omics‐based cancer detection models, a novel liquid biopsy‐based multi‐omics combined model is developed for the early detection of gynecological malignancies. By integrating cell‐free DNA methylation and tumor protein markers, the combined model demonstrates high specificity and sensitivity and is uniquely designed ...
Zheng Feng   +17 more
wiley   +1 more source

Interventions to improve access to care for abnormal uterine bleeding: A systematic scoping review

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 38-48, January 2023., 2023
Abstract Background Women with abnormal uterine bleeding (AUB) experience barriers to accessing healthcare services. Objectives To identify and describe the evidence on interventions to improve healthcare access of women with AUB. Search strategy A systematic search of databases including Medline, CINAHL, EMBASE, Scopus, and Cochrane register for ...
Parimala Suganthini Kanagasabai   +4 more
wiley   +1 more source

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

open access: yesAdvanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang   +17 more
wiley   +1 more source

Sentinel lymph node mapping in endometrial cancer: A comparison of main national and international guidelines

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 220-225, January 2023., 2023
Abstract Objectives To compare national and international guidelines regarding sentinel lymph node (SLN) mapping in endometrial cancer. Methods A descriptive comparative study of the National Comprehensive Cancer Network (NCCN), the Society of Gynecologic Oncology (SGO), the European Society of Gynecological Oncology (ESGO), the British Gynecological ...
Aharon Dick   +5 more
wiley   +1 more source

DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer

open access: yesTumor Biology, 2017
New reliable approaches to stratify patients with endometrial cancer into risk categories are highly needed. We have recently demonstrated that DJ-1 is overexpressed in endometrial cancer, showing significantly higher levels both in serum and tissue of ...
Annalisa Di Cello   +10 more
doaj   +1 more source

RADIA: RNA and DNA Integrated Analysis for Somatic Mutation Detection [PDF]

open access: yes, 2014
The detection of somatic single nucleotide variants is a crucial component to the characterization of the cancer genome. Mutation calling algorithms thus far have focused on comparing the normal and tumor genomes from the same individual. In recent years, it has become routine for projects like The Cancer Genome Atlas (TCGA) to also sequence the tumor ...
arxiv   +1 more source

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