Results 91 to 100 of about 141,167 (306)

Adiposity and endometrial cancer risk in postmenopausal women: a sequential causal mediation analysis [PDF]

, 2020
BACKGROUND: Adiposity increases endometrial cancer risk, possibly through inflammation, hyperinsulinemia, and increasing estrogens. We aimed to quantify the mediating effects of adiponectin (anti-inflammatory adipocytokine); IL6, IL1-receptor antagonist,
Tjonneland, Anne, Allen, Naomi, Moreno-Betancur, Margarita, Ferrari, Pietro, Schulze, Matthias Bernd (Prof. Dr.), Viallon, Vivian, Agudo, Antonio, Christakoudi, Sofia, Dashti, S. Ghazaleh, Weiderpass, Elisabete, Karahalios, Amalia, Simpson, Julie A., Simpson, Julie A, Tsilidis, Konstantinos K., Dahm, Christina C, Riboli, Elio, Tumino, Rosario, Allen, Naomi E, Halkjaer, Jytte, Dashti, S Ghazaleh, Halkjær, Jytte, Hiensch, Anouk E, May, Anne M, Rinaldi, Sabina, Sieri, Sabina, Tsilidis, Konstantinos K, Ardanaz, Eva, Masala, Giovanna, Kaaks, Rudolf, Panico, Salvatore, Schulze, Matthias B, English, Dallas R., Vistisen, Helene Tilma, Aleksandrova, Krasimira, Macciotta, Alessandra, Hiensch, Anouk E., Fortner, Renée Turzanski, Quiros, J. Ramon, May, Anne M., Quirós, J Ramón, Dahm, Christina C., Menegaux, Florence, Aleksandrova, Krasimira (Dr.), English, Dallas R, Severi, Gianluca, Tjønneland, Anne, Allen, Naomi E., Biessy, Carine, Sánchez, Maria-Jose, Dossus, Laure, Amiano, Pilar, Perduca, Vittorio, Colorado-Yohar, Sandra, Gunter, Marc J, Gunter, Marc J.   +54 more
core   +2 more sources

Application value of BHLHE22 and CDO1 gene methylation detection in endometrial cancer screening

徐州医科大学学报
Objective To investigate the clinical application value of BHLHE22 and CDO1 gene methylation detection in cervical exfoliated cells for diognosis of endometrial cancer.
LIU Mingmin, ZHENG Yaru, LI Guilin, HUANG Ruliang   +3 more
doaj   +1 more source

The Role of Metabolic Syndrome in Endometrial Cancer: A Review

Frontiers in Oncology, 2019
Endometrial cancer is one of the most common cancers of the female reproductive system. Although surgery, radiotherapy, chemotherapy, and hormone therapy can significantly improve the survival of patients, the treatment of patients with very early ...
Xiao Yang, Jianliu Wang
doaj   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Anti-Mullerian hormone and endometrial cancer : a multi-cohort study [PDF]

, 2017
Background: The Mullerian ducts are the embryological precursors of the female reproductive tract, including the uterus; anti-Mullerian hormone (AMH) has a key role in the regulation of foetal sexual differentiation.
Antonia Trichopoulou, Xiao-Ou Shu, Johnson, TS, Onland-Moret, NC, Fortner, RT, Merritt, Melissa A., Patrick M Sluss, Allen, Naomi, Onland-Moret, N Charlotte, Jung, S, Lundin, E, Paul N Staats, Joanne F Dorgan, Schock, H, Palli, D, Brian L Egleston, Johnson, Theron S, Seungyoun Jung, Falk, Roni T, Weiderpass, Elisabete, Idahl, A, Naomi E Allen, Melissa A Merritt, Turzanski-Fortner, Renée, Johnson, Theron S., Helzlsouer, Kathy J., Zeleniuch-Jacquotte, Anne, Helzlsouer, Kathy J, Egleston, BL, Schock, Helena, Trichopoulou, Antonia, Annika Idahl, Palli, Domenico, Kathy J Helzlsouer, Arslan, AA, Navarro, C, Shu, XO, Staats, PN, Sluss, Patrick M., Eva Lundin, Vittorio Krogh, Rudolf Kaaks, Helena Schock, Kaaks, Rudolf, Krogh, Vittorio, Carmen Navarro, Weiderpass, E, Falk, RT, Zeleniuch-Jacquotte, A, Egleston, Brian L., Dorgan, JF, Brinton, Louise A, Lundin, Eva, Domenico Palli, Louise A Brinton, Helzlsouer, KJ, Anne Zeleniuch-Jacquotte, Shu, Xiao-Ou, Zheng, Wei, Arslan, Alan A, Idahl, Annika, Renée T Fortner, Krogh, V, Brinton, LA, Zheng, W, Marc J Gunter, Dorgan, Joanne F., Merritt, MA, Sluss, PM, N Charlotte Onland-Moret, Shu, Xiao Ou, Allen, Naomi E., Brinton, Louise A., Allen, NE, Navarro, Carmen, Alan A Arslan, Elisabete Weiderpass, Wei Zheng, Trichopoulou, A, Roni T Falk, Jung, Seungyoun, Falk, Roni T., Fortner, Renée, Theron S Johnson, Kaaks, R, Arslan, Alan A., Fortner, Renée T., Onland-Moret, N. Charlotte, Gunter, Marc J., Staats, Paul N., Gunter, MJ   +90 more
core   +2 more sources

Development and validation of hypermethylated gene markers in cervical cytological samples for detecting endometrial cancer (EndoMethy-I trial)

Frontiers in Oncology
ObjectivesTo explore hypermethylated gene markers in cervical scraped cells that may be associated with endometrial cancer and validate their diagnostic role in endometrial cancer.MethodsIn an exploratory cohort consisting of 40 paired endometrial tissue
Xiaojing Chen, Xiaojing Chen, Xiaojing Chen, Lixin Liu, Lixin Liu, Lixin Liu, Xitong Jin, Xitong Jin, Xitong Jin, Yanan Cheng, Yanan Cheng, Yanan Cheng, Huanwen Wu, Yan You, Yuligh Liou, Yuligh Liou, Pei Liu, Jinghe Lang, Jinghe Lang, Jinghe Lang, Lei Li, Lei Li, Lei Li   +22 more
doaj   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

FGFR2 as a molecular target in endometrial cancer [PDF]

, 2009
Although molecularly targeted therapies have been effective in some cancer types, no targeted therapy is approved for use in endometrial cancer.
Byron, Sara A., Pollock, Pamela M.
core   +1 more source

Risk Factors for Endometrial Cancer in the World: A Narrative Review of the Recent Literature

Clinical and Experimental Obstetrics & Gynecology
Objective: Endometrial cancer is the sixth most common cancer in women. Extensive studies have been conducted around the world to determine the risk factors of endometrial cancer.
Hamid Salehiniya, Leila Allahqoli, Zohre Momenimovahed   +2 more
doaj   +1 more source

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source