Results 71 to 80 of about 141,167 (306)

Anxiety and stress in women with suspected endometrial cancer: Survey and paired observational study [PDF]

, 2021
Objective To determine the anxiety and stress levels of women with suspected endometrial cancer and factors affecting this. Methods Prospective survey and paired observational study of consecutive women with suspected endometrial cancer in a rapid ...
Hughes, Cathy, Yazbek, Joseph, Diana Marcus, Marcus, Diana, King, Alex, Alex King, Ghaem-Maghami, Sadaf, Joseph Yazbek, Sadaf Ghaem‐Maghami, Cathy Hughes   +9 more
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Endometrial and cervical cancer: incidence and mortality among women in the Lodz region [PDF]

, 2015
Introduction: By the early 21st century the most common cancer of female genitals in Poland was cervical cancer. Now endometrial cancer ranks first.
Piotr Woźniak, Beata Leśniczak, Przemysław Oszukowski, Tomasz Stetkiewicz, Grzegorz Krasomski   +4 more
core   +1 more source

Outcome and Radiotherapy Side Effects of High-Risk Endometrial Cancer [PDF]

, 2020
The endometrial cancer is radiosensitive. Adjuvant radiotherapy is previously said that it may improve survival rate of high-risk endometrial cancer and decrease recurrences rate. This study evaluated overall survival, disease-free survival (DFS) in high
Lulus Handayani, M. Dimas Abdi Putra, Brahmana Askandar   +2 more
core   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Evaluation of Preoperative Hematological Parameters in Patients with Endometrial Adenocarcinoma

Bagcilar Medical Bulletin, 2023
Objective:The aim of the study was to compare mean platelet volume (MPV), platelet distribution width (PDW), neutrophil/lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), eosinophil-lymphocyte ratio (ELR), platelet/lymphocyte ratio (PLR) between ...
Serkan Kumbasar, Dilruba Karaca, Fatma Ketenci Gencer, Özlem Khatip, Hatice Yaşat Nacar, Nazime Binnur Cömert, Esra Nazlı Döktür   +6 more
doaj   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

Prognostic factors for rural endometrial cancer patients in a population-based cohort

BMC Public Health, 2019
Background Endometrial cancer is the second most common cancer among female cancer survivors in the US and is increasing in incidence. Rural endometrial cancer patients experience lower survival rates but the reasons for the lower survival are not known.
Brenna E. Blackburn, Sean Soisson, Kerry Rowe, John Snyder, Alison Fraser, Vikrant Deshmukh, Michael Newman, Ken Smith, Kimberly Herget, Anne C. Kirchhoff, Deanna Kepka, Theresa L. Werner, David Gaffney, Kathi Mooney, Mia Hashibe   +14 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Oral contraception and risk of endometrial cancer [PDF]

, 2011
Alfred O Mueck1, Harald Seeger1, Xiangyan Ruan2 1Department of Endocrinology and Menopause, University Women's Hospital of Tuebingen, Tuebingen, Germany; 2Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital ...
Seeger H, Ruan X, Mueck AO
core