Results 61 to 70 of about 3,374,023 (302)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

DDIAS promotes endometrial cancer progression via β-catenin signaling.

PLoS ONE
BackgroundDDIAS has been recognized as an oncogene in various cancers, but its role in endometrial cancer remains unexplored.MethodsThe expression of DDIAS in normal endometrium and endometrial cancer samples was analysed via the The Cancer Genome Atlas (
Xiaojuan Tian, Menglu Liu, Jiangbo Zhao, Chusi Lao, Boya Liu, Yuping Suo   +5 more
doaj   +1 more source

Clinical Value Evaluation of SKA3 in Endometrial Cancer and Its Promotion of Proliferation and Migration of Endometrial Cancer Cells

Clinical and Experimental Obstetrics & Gynecology
Background: Endometrial cancer is one of the common cancers in gynecology, which seriously endangers women’s reproductive health. Therefore, it is urgent to search for new diagnostic and prognostic monitoring markers for endometrial ...
Xiaoxing Ding, Yue Zhang, Jiayun Qin, Yu Zhang, Jinwei Zhang   +4 more
doaj   +1 more source

Cancer-Associated Fibroblasts Promote Proliferation of Endometrial Cancer Cells

, 2019
Western blot analysis of phosphorylated-Akt (Ser473) and phosphorylated-Erk in endometrial cancer cells ECC-1, after treatment with the secretion of normal endometrial fibroblast (T-HESC) or cancer-associated fibroblasts (EC6-Fib, EC7-Fib, EC11-Fib and ...
Ivy Chung (7370150), Zahurin Mohamed (386148), Noor Azmi Mat Adenan (7478283), Seng Tian Tham (7478281), Kavita S. Subramaniam (438295), Woo Yin Ling (7148069)   +5 more
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

FGFR2 as a molecular target in endometrial cancer [PDF]

, 2009
Although molecularly targeted therapies have been effective in some cancer types, no targeted therapy is approved for use in endometrial cancer.
Byron, Sara A., Pollock, Pamela M.
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The significance of markers in the diagnosis of endometrial cancer

, 2016
Endometrial cancer is one of the most common cancers experienced by women throughout the world. It is also the most common malignancy within the female reproductive system, representing 37.7% of all disorders.
Monika M. Żyła, Jacek R. Wilczyński, Marek Nowak, Tomasz Stetkiewicz, Kinga Księżakowska-Łakoma, Grzegorz Stachowiak, Krzysztof Szyłło, Marta Kostrzewa   +7 more
core   +1 more source

Risk factors for endometrial cancer: An umbrella review of the literature [PDF]

, 2018
Although many risk factors could have causal association with endometrial cancer, they are also prone to residual confounding or other biases which could lead to over‐ or underestimation.
Kyrgiou, Maria, Gabra, H, Martin‐Hirsch, P, Kalliala, I, Markozannes, G, Paraskevaidis, E, Nautiyal, J, Cividini, S, Raglan, O, Tsilidis, KK, Gunter, MJ   +10 more
core   +1 more source