Results 61 to 70 of about 212,484 (305)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
DDIAS promotes endometrial cancer progression via β-catenin signaling.
PLoS ONEBackgroundDDIAS has been recognized as an oncogene in various cancers, but its role in endometrial cancer remains unexplored.MethodsThe expression of DDIAS in normal endometrium and endometrial cancer samples was analysed via the The Cancer Genome Atlas (
Xiaojuan Tian +5 more
doaj +1 more source
Systemic Therapy in Endometrial Cancer: Recent Advances. [PDF]
, 2013 Endometrial cancer is a chemosensitive disease. Studies have established a clear benefit of chemotherapy in advanced stages and trials are ongoing to define its role in early stages as well.
Bhise, R +5 more
core +1 more source
Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience. [PDF]
, 2016 BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti ...
Apple, Sophia K +5 more
core +2 more sources
Clinical and Experimental Obstetrics & GynecologyBackground: Endometrial cancer is one of the common cancers in gynecology, which seriously endangers women’s reproductive health. Therefore, it is urgent to search for new diagnostic and prognostic monitoring markers for endometrial ...
Xiaoxing Ding +4 more
doaj +1 more source
Fertility preservation in gynaecologic cancers [PDF]
, 2018 Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and ...
De Felice, Francesca +9 more
core +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
Advanced Materials, EarlyView.A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
, 2018 Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
DJ-1 is a reliable serum biomarker for discriminating high-risk endometrial cancer
Tumor Biology, 2017 New reliable approaches to stratify patients with endometrial cancer into risk categories are highly needed. We have recently demonstrated that DJ-1 is overexpressed in endometrial cancer, showing significantly higher levels both in serum and tissue of ...
Annalisa Di Cello +10 more
doaj +1 more source