Results 41 to 50 of about 3,374,023 (302)
A Metabolic-Epigenetic Axis of AARS1/IGF2BP3-K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence. [PDF]
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Jiang P +11 more
europepmc +2 more sources
Accuracy of Pre-operative Endometrial Sampling for the Detection of High Grade Endometrial Cancer
Objective:To assess the accuracy of endometrial sampling for detection of high grade endometrial cancer.Materials and Methods: This study was a diagnostic test.
Uraiwan Khomphaiboonkij +1 more
doaj +1 more source
Survival outcome in endometrial cancer patients according to hereditary predisposition
Objective: A familial history of ovarian cancer/breast cancer is considered a significant prognostic factor for ovarian cancer. We investigated hereditary factors by examining the incidence of synchronous malignancy in patients with endometrial cancer ...
Heon Jong Yoo +7 more
doaj +1 more source
. Background. Endometrial cancer is one of the most common malignancies of the reproductive system. Effective and cost-effective screening method for populations at high risk is not available.
Guo Zhang +8 more
doaj +1 more source
Patterns of care and outcomes for endometrial and ovarian cancers in botswana 2015–2021
Purpose: Endometrial and ovarian cancers are leading causes of cancer death among women. However, there is little data on these patients from low- and middle-income countries including Botswana, a country in sub-Saharan Africa. This study reports data on
Christian Lumley +13 more
doaj +1 more source
Insulin and Endometrial Cancer [PDF]
Elevated insulin levels may explain part of the increased risk of endometrial cancer observed in obese postmenopausal women. Circulating sex hormones and fasting C-peptide levels were measured in sera obtained from 165 postmenopausal endometrial cancer cases accrued between June 1, 1987, and May 15, 1990, from hospitals in Chicago, Illinois; Hershey ...
R, Troisi +4 more
openaire +2 more sources
The identification of target genes at genome-wide association study (GWAS) loci is a major obstacle for GWAS follow-up. To identify candidate target genes at the 16 known endometrial cancer GWAS risk loci, we performed HiChIP chromatin looping analysis ...
Dylan M. Glubb +3 more
core +1 more source
Analysis of lncRNA sequences: FAM3D-AS1, LINC01230, LINC01315 and LINC01468 in endometrial cancer
Background The analysis of long non-coding RNA (lncRNA) in endometrial cancer is a novel field of science. Although numerous lncRNA sequences have been identified until today, their correlation with endometrial cancer is still undetermined.
Jan Bieńkiewicz +7 more
doaj +1 more source
MicroRNAs in endometrial cancer [PDF]
MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) of approximately 22 bp that induce RNA interference with a complementary messenger RNA (mRNA) and act in silencing of mRNA. miRNAs are strongly associated with cancer development and those involved in carcinogenesis are classified into oncogenic miRNAs and tumor suppressor miRNAs (tumor ...
Kouji, Banno +5 more
openaire +2 more sources
Identify the predisposition genes to endometrial cancer
[[abstract]]Endometrial carcinoma is the most dominant gynecological tumor worldwide. Familial risk of endometrial cancer has been reported but little is known about the predisposition genes.
Chiang, YC;Lee, TF;Lin, YF;Weng, HY;Tsai, SF;Wu, CW
core +1 more source

