Results 21 to 30 of about 212,484 (305)

Mutations and amplification of oncogenes in endometrial cancer [PDF]

, 1999
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang, Beckmann, Matthias W., Bender, Hans G., Cho, Yong-Jig, Hantschmann, Peer, Niederacher, Dieter   +5 more
core   +1 more source

Unique Molecular Features in High-Risk Histology Endometrial Cancers [PDF]

, 2019
Endometrial cancer is the most common gynecologic malignancy in the United States and the sixth most common cancer in women worldwide. Fortunately, most women who develop endometrial cancer have low-grade early-stage endometrioid carcinomas, and simple ...
Collins, Kaitlyn, Hawkins, Shannon M., Jones, Devin E., Pandita, Pooja, Wang, Xiyin   +4 more
core   +1 more source

ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

Scientific Reports, 2021
In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah, Yahya Elshimali, Alison Chu, Neda A. Moatamed, Jamar P. Uzzell, Jessica Tsui, Stephen Schettler, Hania Shakeri, Madhuri Wadehra   +8 more
doaj   +1 more source

Endometrial cancer following endometrial resection [PDF]

Gynecological Surgery, 2007
Endometrial ablation has emerged as a viable alternative to hysterectomy in the treatment of medically intractable dysfunctional uterine bleeding. However, this procedure cannot guarantee complete removal of the entire endometrium. Cases of endometrial cancer after endometrial ablation have been reported in the literature.
Giorgia Gaia, Revaz Botchorishvili, Michel Canis, Benoit Rabischong, Kris Jardon, Juan Real Escalona, Guy Lesec, Frederic Penault-Llorca, Pierre Dechelotte, Jean Luc Pouly, Gérard Mage   +10 more
openaire   +1 more source

Relationship between duration of breast feeding and endometrial cancer: a case-control study [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Endometrial cancer is the most common gynecologic malignancy in developed countries. The incidence of endometrial cancer is increasing in Iran. The risk of endometrial cancer is related to estrogen levels that breastfeeding reduces it. This
Zohreh Yeganeh, Zohreh Sheikhan, Parastoo Hajian, Taraneh Esteki, Malihe Nasiri, Nahid Khodakarami   +5 more
doaj   +1 more source

Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. [PDF]

, 2014
Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects on HNF1B gene ...
Aida K. Dieffenbach, Alexander Hein, Alfons Meindl, Alison M. Dunning, Amanda B. Spurdle, Angel Carracedo, Angela Cox, Angela Jones, Anja Rudolph, Anjali K. Henders, Anne-Lise Børresen-Dale, Annika Lindblom, Anthony J. Swerdlow, Arif B. Ekici, Attila Teoman, Augusto Rojas-Martinez, Bach, Bahcall, Barbara Burwinkel, Berndt, Boris Winterhoff, Brooke L. Fridley, Buchanan, Buchner, Cancer Genome Atlas Research Network, Cancer Genome Atlas Research, N, Carina Walpole, Catherine S. Healey, Cerami, Cuff, Dale R. Nyholt, Deborah J. Thompson, Diether Lambrechts, Douglas F. Easton, Dunham, Edwards, Eeles, Eeles, Eger, Elizabeth Holliday, Ellen L. Goode, Emma Tham, Erika Santos, Felicity A. Lose, Fergus J. Couch, Ferreira, Fiona Bruinsma, Frederic Amant, Frederik Marme, Gao, Garcia-Closas, Garg, Gauderman, Geoffrey Otton, Gerasimos Tzortzatos, Glinsky, Graham G. Giles, Grant W. Montgomery, Grisanzio, Gudmundsson, Harries, Helga B. Salvesen, Henrica M.J. Werner, Hermann Brenner, Higgins, Hiltrud Brauch, Houlston, Howie, Howie, Hughes, Ian Tomlinson, Ingo Runnebaum, Janet E. Olson, Jenny Chang-Claude, Jeroen Depreeuw, Jianjun Liu, Jingmei Li, Jirong Long, Jodie N. Painter, Joe Dennis, John Attia, John L. Hopper, Jonathan P. Tyrer, Jone Trovik, Julian Peto, Julie M. Cunningham, Juliet D. French, Jyotsna Batra, Kaltin Ferguson, Kamila Czene, Katie Ashton, Kimberley Howarth, Kristine M. Hillman, Kyriaki Michailidou, Lazarevich, Leire Moya, Lieve Coenegrachts, Liu, Long, Luis Carvajal-Carmona, Lynn Martin, Ma. Magdalena Echeverry De Polanco, Macintyre, Maggie Gorman, Manjeet K. Bolla, Manuel R. Teixeira, Mark McEvoy, Matthias Dürst, Matthias Ruebner, Matthias W. Beckmann, Matthieu Moisse, McEvoy, McGregor, Melissa C. Southey, Michailidou, Miriam Mints, Mitul Shah, Monica Sans, Nicholas G. Martin, Nicholas Orr, Nicola Johnson, Painter, Pamela Pollock, Paul D.P. Pharoah, Penelope M. Webb, Per Hall, Peter A. Fasching, Peter Hillemanns, Pharoah, Pruim, Qin Wang, Rachel Palmieri Weber, Rodney J. Scott, Sakoda, Sean C. Dowdy, Sergi Castellvi-Bel, Shahana Ahmed, Shao, Shen, Shirley Hodgson, Singh, Spoelstra, Spurdle, Stacey L. Edwards, Stefan P. Renner, Stefanie Schrauwen, Sun, Susanne Kaufmann, Takata, Tavassoli, Teo, Terasawa, Thilo Dörk, Thomas, Timothy Cheng, Tony Proietto, Tormund S. Njolstad, Tracy A. O'Mara, Tsuchiya, Udler, Vessela N. Kristensen, Wei Zheng, Wellcome Trust Case Control Consortium, Xiao-Ou Shu, Yong-Bing Xiang, Zhihua Chen   +165 more
core   +7 more sources

Association between diabetes, diabetes treatment and risk of developing endometrial cancer. [PDF]

, 2014
BackgroundA growing body of evidence suggests that diabetes is a risk factor for endometrial cancer incidence. However, most of these studies used case-control study designs and did not adjust for obesity, an established risk factor for endometrial ...
Beresford, S, Chen, C, Chlebowski, R, Garcia, L, Kuller, L, Luo, J, Margolis, KL, Regier, M, Wactawski-Wende, J   +8 more
core   +2 more sources

Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]

, 2014
Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa, Bryk, Jarek, Futyma, Konrad, Lorenc, Anna, Miotla, Pawel, Putowski, Lechoslaw, Semczuk, Andrzej   +6 more
core   +1 more source

Immunophenotype of Atypical Polypoid Adenomyoma of the Uterus: Diagnostic Value and Insight on Pathogenesis [PDF]

, 2020
Atypical polypoid adenomyoma (APA) is a rare uterine lesion constituted by atypical endometrioid glands, squamous morules, and myofibromatous stroma. We aimed to assess the immunophenotype of the 3 components of APA, with regard to its pathogenesis and ...
Aggarwal, Ayhan, Chiarelli, Di Palma, Fukunaga, Giampaolino, Heatley, Horita, Houghton, Jiang, Kuwashima, Lin, Longacre, Lu, Ma, Mazur, McAlpine, McCluggage, McCluggage, Moher, Nei, Nomura, Nomura, Němejcová, Ohishi, Ota, Raffone, Raffone, Raffone, Raffone, Raffone, Raffone, Ramos, Stelloo, Strickland, Takahashi, Talhouk, Terada, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Travaglino, Young, Zhang   +46 more
core   +1 more source

Type II transmembrane serine proteases 4 (TMPRSS4) promotes proliferation, invasion and epithelial–mesenchymal transition in endometrial carcinoma cells (HEC1A and Ishikawa) via activation of MAPK and AKT

Animal Cells and Systems, 2021
Endometrial cancer is the most common gynecological cancer in the developed countries. Type II transmembrane serine proteases 4 (TMPRSS4) is a newly discovered transmembrane protein, which may be related to the invasion, metastasis of the tumor and the ...
Huan Xiao, Zhian Zhang, Dan Peng, Chunqing Wei, Benling Ma   +4 more
doaj   +1 more source