Results 11 to 20 of about 3,374,023 (302)
Endometrial cancer
JAAPA, 2022 Endometrial cancer is the most common gynaecological cancer in high income countries and its incidence is rising globally. Although an ageing population and fewer benign hysterectomies have contributed to this trend, the growing prevalence of obesity is the major underlying cause.Crosbie, Emma J, Kitson, Sarah J; id_orcid 0000-0003-2763-7370, Mcalpine, Jessica N, Mukhopadhyay, Asima, Powell, Melanie E, Singh, Naveena +5 moreopenaire +5 more sourcesEndometrial cancer [PDF]
Best Practice & Research Clinical Obstetrics & Gynaecology, 2012 Endometrial carcinoma is the most common gynaecological malignancy in the Western world. The standard management of endometrial carcinoma is total hysterectomy and bilateral salpingo-oophorectomy with or without pelvic and para-aortic lymph-node dissection.Vivek, Arora, Michael A, Quinnopenaire +4 more sourcesEndometrial cancer [PDF]
The Lancet, 2016 Endometrial cancer is the most common gynaecological tumour in developed countries, and its incidence is increasing. The most frequently occurring histological subtype is endometrioid adenocarcinoma. Patients are often diagnosed when the disease is still confined to the uterus.Morice, P., Leary, A., Creutzberg, C., Abu-Rustum, N., Darai, E. +4 moreopenaire +5 more sourcesp190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer-relevant paralog interplay. [PDF]
Mol OncolThis study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.Pinault M, Heraud C, Oliveira MC, Neaud V, Valesco V, Prouzet-Mauleon V, Turcq B, Dupuy JW, Raymond AA, Croce S, Saltel F, Lagrée V, Moreau V. +12 moreeuropepmc +2 more sourcesCigarette smoking and endometrial cancer risk: observational and mendelian randomization analyses [PDF]
, 2022 Background:
Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, Tjonneland, Anne, Simeon, Vittorio, Fortner, RT, Gram, IT, Christina C. Dahm, Crous-Bou, M, Aglago, Elom K.,, Perez-Cornago, Aurora, Bondonno, Nicola P., Braaten, Tonje, Bergmann, Manuela M., Schulze, Matthias Bernd (Prof. Dr.), Viallon, Vivian, Crous-Bou, Marta,, Tagliabue, Giovanna,, Palli, D, Bondonno, Nicola P.,, Tjønneland, A, Omiyale, W, Braaten, T, Nøst, Therese Haugdahl, Palli, Domenico, Heath, Alicia K., Tagliabue, G, Allen, Naomi E, Omiyale, Wemimo,, Simeon, Vittorio,, Gram, Inger T., Schulze, MB, Sacerdote, Carlotta, Rudolf Kaaks, Colorado-Yohar, Sandra M., Dahm, Christina C.,, Heath, Alicia K.,, Giovanna Tagliabue, Dossus, Laure,, Kaaks, Rudolf, Matthias B. Schulze, Viallon, V, Carine Biessy, Carlotta Sacerdote, Perez-Cornago, Aurora,, Rosario Tumino, Bondonno, NP, Domenico Palli, Ardanaz, E, Severi, G, Dimou, Niki,, Braaten, Tonje,, Crous-Bou, Marta, Thérèse Truong, Perez-Cornago, A, Biessy, Carine,, Eva Ardanaz, Idahl, Annika, Tonje Braaten, Laure Dossus, Dimou, Niki, Severi, Gianluca, Tjønneland, Anne, Allen, Naomi E., Lacey, Ben,, Weiderpass, Elisabete,, Colorado-Yohar, Sandra M, Johansson, Mattias, Harlid, S, Biessy, C, Gram, Inger T.,, Viallon, Vivian,, Truong, Thérèse,, Niki Dimou, Simeon, V, Sánchez, Maria-Jose, Inger T. Gram, Bondonno, Nicola P, Murphy, N, Manuela M. Bergmann, Schulze, Matthias B.,, Sophia Harlid, Anne Tjønneland, Bergmann, MM, Kvaskoff, M, Gunter, Marc J, Gunter, Marc J., Alicia K. Heath, Nøst, Therese H, Kvaskoff, Marina,, Tjønneland, Anne,, Gunter, Marc J.,, Sánchez, Maria-Jose,, Harlid, Sophia, O’Mara, Tracy A., Palli, Domenico,, Sacerdote, Carlotta,, O'Mara, Tracy A, Lacey, Ben, Dossus, L, Aglago, Elom K., Weiderpass, Elisabete, Colorado-Yohar, SM, Idahl, A, Schulze, Matthias B., O'Mara, Tracy A.,, Allen, Naomi E.,, Renée T. Fortner, Kaaks, Rudolf,, Wemimo Omiyale, Aglago, Elom K, Annika Idahl, Aglago, EK, Lacey, B, Kim Overvad, Dahm, Christina C, Harlid, Sophia,, Naomi E. Allen, Gram, Inger T, Tumino, Rosario, Marina Kvaskoff, Johansson, M, Bergmann, Manuela M, Dahm, CC, Gram, Inger Torhild, Nøst, Therese H.,, Vittorio Simeon, Sandra M. Colorado-Yohar, Murphy, Neil,, Tagliabue, Giovanna, Maria-Jose Sánchez, Neil Murphy, Ardanaz, Eva, Heath, Alicia K, Overvad, Kim,, Weiderpass, E, Schulze, Matthias B, Tumino, Rosario,, Marta Crous-Bou, Ben Lacey, Nøst, Therese H., Kvaskoff, Marina, Elom K. Aglago, Aurora Perez-Cornago, Truong, T, Therese H. Nøst, Colorado-Yohar, Sandra M.,, Dahm, Christina C., Dimou, N, Fortner, Renée T, Overvad, Kim, Overvad, K, Sanchez-Perez, Maria-Jose, Omiyale, Wemimo, Idahl, Annika,, Heath, AK, Sacerdote, C, Murphy, Neil, Allen, NE, Mattias Johansson, Marc J. Gunter, Nøst, TH, Biessy, Carine, Truong, Thérèse, Elisabete Weiderpass, Johansson, Mattias,, Severi, Gianluca,, Dossus, Laure, Sánchez, MJ, Gianluca Severi, Tumino, R, O'Mara, Tracy A., Nost, Therese H., Nicola P. Bondonno, Kaaks, R, Fortner, Renée T., Ardanaz, Eva,, O'Mara, TA, Bergmann, Manuela M.,, Vivian Viallon, Fortner, Renée T,, Tracy A. O'Mara, Gunter, MJ, Kvaskoff M., Sanchez M. -J., Tjonneland A., Dimou N., Bergmann M. M., Bergmann, Manuela M. (PhD), O'Mara T. A., Dahm C. C., Palli D., O'Mara, Tracy A., Harlid S., Fortner R. T., Biessy C., Simeon V., Lacey B., Sánchez, Maria José, Aglago E. K., Kaaks R., Murphy N., Gunter M. J., Overvad K., Colorado-Yohar S. M., Truong T., Johansson M., O'Mara, Tracy A, Allen N. E., Colorado-Yohar, Sandra, Sánchez Pérez, María José, Nost T. H., Schulze M. B., Tumino R., Bondonno N. P., Crous-Bou M., Heath A. K., Braaten T., Weiderpass E., Pérez Cornago, Aurora, Perez-Cornago A., Idahl A., Viallon V., Omiyale W., Gram I. T., Sacerdote C., Ardanaz E., Dossus L., Tagliabue G., Severi G., Crous Bou, Marta +227 morecore +1 more sourceMutations and amplification of oncogenes in endometrial cancer [PDF]
, 1999 Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...Niederacher, Dieter, Cho, Yong-Jig, An, Han-Xiang, Beckmann, Matthias W., Hantschmann, Peer, Bender, Hans G. +5 morecore +1 more sourceMicroRNA-135a promotes proliferation, migration, invasion and induces chemoresistance of endometrial cancer cells
European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2020 Aims: MicroRNAs play essential roles in tumorigenesis and progression in various cancers including endometrial cancer. Here we assessed the role of miR-135a on proliferation, chemosensitivity, migration and invasion of endometrial cancer cells.Jiping Wang, Li Zhang, Wenyan Jiang, Rongkui Zhang, Bei Zhang, Aidaeraili Silayiding, Xiumei Duan +6 moredoaj +1 more sourcePDIA6, which is regulated by TRPM2-AS/miR-424-5p axis, promotes endometrial cancer progression via TGF-beta pathway
Cell Death and Disease, 2023 PDIA6 have been reported to be involved in a variety of cancers, however, the underlying role in endometrial cancer is still unclear. In this study, we aimed to study the function of PDIA6 in endometrial cancer.Pengling Wang, Tianli Zhang, Nan Jiang, Kun Wang, Liping Feng, Ting Liu, Xingsheng Yang +6 moredoaj +1 more sourceEndometrial cancer
The Lancet, 2005 Each year, endometrial cancer develops in about 142,000 women worldwide, and an estimated 42,000 women die from this cancer. The typical age-incidence curve for endometrial cancer shows that most cases are diagnosed after the menopause, with the highest incidence around the seventh decade of life. The appearance of symptoms early in the course explains Amant, Frédéric, Moerman, Philippe, Neven, Patrick, Timmerman, Dirk, Van Limbergen, Erik, Vergote, Ignace +5 moreopenaire +6 more sources
