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In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but
Vei Mah +8 more
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Body mass index, hormone replacement therapy, and endometrial cancer risk: a meta-analysis [PDF]
Background: Body mass index (BMI) is a risk factor for endometrial cancer. We quantified the risk and investigated whether the association differed by use of hormone replacement therapy (HRT), menopausal status, and histologic type. Methods: We searched
Crosbie, Emma J +14 more
core +1 more source
Endometrial Hyperplasia and Endometrial Carcinoma [PDF]
Endometrial hyperplasia and endometrial carcinoma are rare in young women, but the incidence is continually increasing in developed countries due to obesity and metabolic diseases.
Wimberger, Pauline +5 more
core +1 more source
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts [PDF]
Lynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2.
Capella, G. +153 more
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FIGO staging of endometrial cancer: 2023 [PDF]
INTRODUCTION: Many advances in the understanding of the pathologic and molecular features of endometrial cancer have occurred since the FIGO staging was last updated in 2009.
Christina Fotopoulou +22 more
core +1 more source
Endometrial cancer is the most common gynecological cancer in the developed countries. Type II transmembrane serine proteases 4 (TMPRSS4) is a newly discovered transmembrane protein, which may be related to the invasion, metastasis of the tumor and the ...
Huan Xiao +4 more
doaj +1 more source
Prognostic value of angiogenic markers of endometrial cancer (literature review)
Endometrial cancer is the most common cancer of the female reproductive organs. The purpose of the study was to summarize the available data on the role of angiogenic markers in the development, progression and prognosis of endometrial cancer.
N. S. Zolotukhina, L. F. Gulyaeva
doaj +1 more source
Background: In women with endometrial hyperplasia, there is a risk for co-existent endometrial cancer when patients are subjected to immediate surgical treatment.
Gokhan Boyraz +4 more
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Prevalence of Co-existing Endometrial Carcinoma in Patients with Preoperative Diagnosis of Endometrial Hyperplasia [PDF]
Introduction: Endometrial hyperplasia has been associated with the presence of concomitant endometrial carcinoma. In this study, patients who were diagnosed with endometrial hyperplasia and had hysterectomy, determination of the incidence of ...
Pinar Kadirogullari +3 more
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Risk Factors for Endometrial Lesions Detected by Hysteroscopy in Breast Cancer Patients Taking Tamoxifen [PDF]
Background Breast cancer has become the most common malignant tumor threatening the health of Chinese women in recent years. The use of tamoxifen (TAM) has successfully reduced the recurrence and progression of estrogen receptor-positive breast cancer ...
LI Yujing, JIN Yichao, CHEN Xing, JI Mengying, DAI Huihua
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