Results 51 to 60 of about 141,167 (306)

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
Annemarie Samalecos, Annemarie Samalecos (275635), Anja Wolf (275636), Weimar, C.H., Philipp Velicky, Michelle Kruse (275634), Wolf Anja, Kruse Michelle, Nick S Macklon, Macklon Nick S., Charlotte H. E. Weimar (148304), Nick S. Macklon (148320), Velicky Philipp, Weimar Charlotte H. E., Maren Schwenke, Philipp Velicky (275632), Gellersen Birgit, Schwenke, M., Maren Schwenke (275628), Knöfler Martin, Schwenke Maren, Gellersen, B., Samalecos Annemarie, Wolf, A., Bamberger, A.M., Martin Knöfler, Anja Wolf, Bamberger Ana-Maria, Michelle Kruse, Charlotte H E Weimar, Birgit Gellersen (148307), Velicky, P., Ana-Maria Bamberger, Ana-Maria Bamberger (275637), Kruse, M., Macklon, N.S., Birgit Gellersen, Knofler, M., Samalecos, A., Martin Knöfler (275630)   +39 more
core   +1 more source

Patterns of care and outcomes for endometrial and ovarian cancers in botswana 2015–2021

Gynecologic Oncology Reports, 2023
Purpose: Endometrial and ovarian cancers are leading causes of cancer death among women. However, there is little data on these patients from low- and middle-income countries including Botswana, a country in sub-Saharan Africa. This study reports data on
Christian Lumley, Samantha Batman, Lisa Bazzett-Matabele, Barati Monare, Memory Bvochora-Nsingo, Sebathu Chiyapo, Rebecca Ketlametswe, Gaborone Mbulawa, Alexander Seiphetlheng, Gaobakwe Ramontshonyane, Tlotlo Ralefala, Rebecca Luckett, Peter Vuylsteke, Surbhi Grover   +13 more
doaj   +1 more source

Correlation of Hypothyroidism and Endometrial Carcinoma

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the relationship between hypothyroidism and endometrial carcinoma, and to explore the relationship of the differentiation degree of endometrial carcinoma, the expression of estrogen receptor (ER) and progesterone receptor (PR) in
LIAO Yuping, YANG Bing
doaj   +1 more source

Analysis of lncRNA sequences: FAM3D-AS1, LINC01230, LINC01315 and LINC01468 in endometrial cancer

BMC Cancer, 2022
Background The analysis of long non-coding RNA (lncRNA) in endometrial cancer is a novel field of science. Although numerous lncRNA sequences have been identified until today, their correlation with endometrial cancer is still undetermined.
Jan Bieńkiewicz, Hanna Romanowicz, Bożena Szymańska, Daria Domańska-Senderowska, Miłosz Wilczyński, Anna Stepowicz, Andrzej Malinowski, Beata Smolarz   +7 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Investigation of dietary factors and endometrial cancer risk using a nutrient-wide association study approach in the EPIC and nurses' health study (NHS) and NHSII [PDF]

, 2015
Data on the role of dietary factors in endometrial cancer development are limited and inconsistent. We applied a "nutrient-wide association study" approach to systematically evaluate dietary risk associations for endometrial cancer while controlling for ...
Tjonneland, Anne, Nilsson, Lena Maria, Merritt, Melissa A., Bueno-De-Mesquita, H. B., Sánchez, María-José, Onland-Moret, N Charlotte, Ericson, Ulrica, Nilsson, Lena Maria,, Tworoger, Shelley S., Salmerón, D, Petersen, Kristina E. N., Quirós, J. Ramón, Weiderpass, Elisabete, Travis, Ruth C., Khaw, Kay-Tee, Barricarte, Aurelio, Salmerón, D., Duell, Eric J, Trichopoulou, Antonia, Fernandes, Judy, Bueno-de-Mesquita, H B As, Tsilidis, Konstantinos K., Palli, Domenico, Dahm, Christina C, Romieu, Isabelle, Riboli, Elio, Chamosa, Saioa, Gram, Inger T, Tumino, Rosario, Patel, Chirag J., Merritt, Melissa A, Peeters, Petra H., Mattiello, Amalia, Tworoger, Shelley S, De Vivo, Immaculata, Gram, Inger T., Boutron-Ruault, Marie Christine, Sacerdote, Carlotta, Duell, Eric J., Rinaldi, Sabina, Tsilidis, Konstantinos K, Bueno-de-Mesquita, H. B. (as), Kaaks, Rudolf, Sonestedt, Emily, Peeters, Petra H, Hankinson, Susan E., Skeie, Guri, Aleksandrova, Krasimira, Petersen, Kristina E N, Patel, Chirag J, Tzoulaki, Ioanna, Trichopoulos, Dimitrios, Idahl, Annika, Quirós, J Ramón, Dahm, Christina C., Overvad, Kim, Fortner, Renée T, Idahl, Annika,, Khaw, Kay Tee, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Grioni, Sara, Wareham, Nicholas, Travis, Ruth C, Dossus, Laure, Hankinson, Susan E, Ramon Quiros, J., Fortner, Renée T., Boeing, Heiner, Onland-Moret, N. Charlotte, Sánchez, María José, Bamia, Christina, Fagherazzi, Guy, Gunter, Marc J., Gunter, Marc J   +74 more
core   +1 more source