Results 121 to 130 of about 234,996 (348)

Expression of the glucagon-like peptide-1 receptor and its role in regulating autophagy in endometrial cancer

BMC Cancer, 2018
Background A previous report showed that a glucagon-like peptide-1 receptor (GLP-1R) agonist (exenatide) induced apoptosis in endometrial cancer cells.
Ranka Kanda, Haruko Hiraike, Osamu Wada-Hiraike, Takayuki Ichinose, Kazunori Nagasaka, Yuko Sasajima, Eiji Ryo, Tomoyuki Fujii, Yutaka Osuga, Takuya Ayabe   +9 more
doaj   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Tumor-suppressor role of miR-139-5p in endometrial cancer

Cancer Cell International, 2018
Background Endometrial cancer (EC) is the fourth most common malignancy of the female genital tract worldwide. MicroRNAs are important gene regulators with critical roles in diverse biological processes, including tumorigenesis. Several study’s show that
JinHui Liu, ChunYu Li, Yi Jiang, YiCong Wan, ShuLin Zhou, WenJun Cheng   +5 more
doaj   +1 more source

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

Comparison of Risk Factors and survival of Type 1 and Type II Endometrial Cancers [PDF]

, 1969
Tahira Y Malik, Uzma Chishti, Aliya Begum Aziz, Sheikh Irfan   +3 more
openalex   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

Advanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua, Rachel C. Quilang, Katja Sallinger, Christina Athena Aktipis, Petra Arck, Diana W. Bianchi, Hyun‐Dong Chang, Henderson J. Cleaves II, Michael Eikmans, Heidi E. S. Fjeldstad, David Haig, Whitney E. Harrington, William Horsnell, Daniel P. Jacobsen, Mads Kamper‐Jørgensen, Sami B. Kanaan, Kiarash Khosrotehrani, Nathalie C. Lambert, Jane Lee Nelson, Maria B. Olsen, Tiffany D. Pan, Jelmer R. Prins, Frank A. Schildberg, Anne Cathrine Staff, Anders Ståhlberg, Ina A. Stelzer, Christopher Urbschat, Sing Sing Way, Melissa A. Wilson, Jody Ye, Thomas Kroneis, Amy M. Boddy   +31 more
wiley   +1 more source

Epidemiology, molecular typing, microbiome-immune interactions and treatment strategies of endometrial cancer: a review

Frontiers in Immunology
This review focuses on the field of endometrial cancer. Since 2020, there have been 417,367 new cases of endometrial cancer diagnosed globally and 97,370 deaths reported.
Bingyan Liang, Bingyan Liang, Jia Tan, Jia Li, Xiaolan Wang, Genlin Li, Huanhuan Li, Ting Li, Hong Gao, Hong Gao, Hong Gao   +10 more
doaj   +1 more source

Endometrial and cervical cancer: incidence and mortality among women in the Lodz region

Menopause Review, 2015
Introduction: By the early 21st century the most common cancer of female genitals in Poland was cervical cancer. Now endometrial cancer ranks first.
Beata Leśniczak, Grzegorz Krasomski, Przemysław Oszukowski, Tomasz Stetkiewicz, Piotr Woźniak   +4 more
doaj   +1 more source

The Value and Pitfalls of Vaginal and Cervical Smears in the Detection of Endometrial and Extra-uterine Cancer: a Reminder [PDF]

, 1968
Robert J. Faulconer
openalex   +1 more source

Surgery for Older Cancer Patients: Cross‐Organ Review and Good Practice Statement by the Japanese Geriatric Oncology Guideline Committee

Annals of Gastroenterological Surgery, EarlyView.
We conducted a cross‐organ review of surgical outcomes in older cancer patients based on literature cited in Japanese clinical guidelines. This study summarizes postoperative complication rates and survival outcomes across five major cancer types. The findings aim to support the development of geriatric oncology surgical guidelines tailored to Japan's ...
Chie Tanaka, Takashi Ofuchi, Kiichiro Ninomiya, Daisuke Inoue, Ken Sugimoto, Keiko Murofushi, Toru Okuyama, Shigeaki Watanuki, Chiyo Imamura, Daisuke Sakai, Naomi Sakurai, Kiyotaka Watanabe, Kazuo Tamura, Toshiaki Saeki, Hiroshi Ishiguro   +14 more
wiley   +1 more source