Results 131 to 140 of about 210,312 (353)
IJU Case Reports, Volume 6, Issue 1, Page 33-36, January 2023., 2023 Introduction In Lynch syndrome, urothelial cancer is the third most common cancer, following colorectal and endometrial cancers. Little is known, however, about the efficacy of immune checkpoint inhibitors in the treatment of metastatic urothelial cancer in Lynch syndrome.
Ryosuke Oki +7 more
wiley +1 more source
BMC Cancer, 2018 Background A previous report showed that a glucagon-like peptide-1 receptor (GLP-1R) agonist (exenatide) induced apoptosis in endometrial cancer cells.
Ranka Kanda +9 more
doaj +1 more source
Transform-Domain Classification of Human Cells based on DNA Methylation Datasets [PDF]
arXiv, 2019 A novel method to classify human cells is presented in this work based on the transform-domain method on DNA methylation data. DNA methylation profile variations are observed in human cells with the progression of disease stages, and the proposal is based on this DNA methylation variation to classify normal and disease cells including cancer cells. The
arxiv
Tamoxifen and Assymptomatic Endometrial Thickness [PDF]
, 2008 Tamoxifen is a first-line agent for adjuvant treatment of estrogen-receptor positive breast cancer, and is used to reduce the risk of this condition in high-risk individuals.
Amaral, N, Fatela, A, Robalo, R
core
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Pathogenic germline variants in the APC gene result in familial adenomatous polyposis (FAP) which can escalate into colon cancer. Standard clinical testing failed to identify pathogenic variants in a 4‐generation FAP family. We identified and assessed co‐segregation of a 5′ untranslated region (UTR) variant, NM_001127511.3 (APC) c.‐40G>A ...
Brendon Young +9 more
wiley +1 more source
17β-Estradiol promotes endometrial cancer proliferation and invasion through IL-6 pathway
Endocrine Connections, 2019 Accumulating evidence revealed that the leading risk factor of endometrial cancer is exposure to endogenous and exogenous estrogens, while the exact mechanism underlying estrogen contribution to endometrial cancer progression has not been elucidated ...
Qi Che +6 more
doaj +1 more source
Net benefit separation and the determination curve: a probabilistic framework for cost-effectiveness estimation [PDF]
arXiv, 2019 Considerations regarding clinical effectiveness and cost are essential in comparing the overall value of two treatments. There has been growing interest in methodology to integrate cost and effectiveness measures in order to inform policy and promote adequate resource allocation.
arxiv
Progestins and endometrial cancer
Gynecological Endocrinology, 2001 Premenopausal women--especially young women--with endometrial cancer stage I may be treated successfully with progestins alone as primary therapy to preserve their child-bearing potential. There is some indication that progestins could be used in neoadjuvant fashion.
openaire +3 more sources
Does cytological laboratory hold the responsibility for the low sensitivity of the Pap test in detecting endometrial cancer? [PDF]
, 2015 Endometrial cancer is the most common gynecological cancer but there is no economically justified screening method. Although we can detect endometrial cells in the sample using PAP test, many studies show low sensitivity and positive predictive value of ...
Igor Tomašković +5 more
core +1 more source
Assessment of sexual difficulties associated with multi-modal treatment for cervical or endometrial cancer: A systematic review of measurement instruments [PDF]
, 2016 Background: Practitioners and researchers require an outcome measure that accurately identifies the range of common treatment-induced changes in sexual function and well-being experienced by women after cervical or endometrial cancer.
Lucas, G. +3 more
core +1 more source