Results 131 to 140 of about 238,870 (356)

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone, Beatrice Cavina, Daniele Gaetano Sirico, Martina Mugnano, Vittorio Bianco, Lisa Miccio, Anna Myriam Perrone, Anna Maria Porcelli, Giuseppe Gasparre, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro   +11 more
wiley   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

Animal Research and One Health, EarlyView.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang, Ao Guo, Lin Zhang, Shengru Wu, Juan Du, Taiyong Yu   +5 more
wiley   +1 more source

Improved preoperative risk stratification with CA-125 in low-grade endometrial cancer: a multicenter prospective cohort study [PDF]

, 2019
Casper Reijnen, Nicole C.M. Visser, Jenneke C. Kasius, Dorry Boll, Peggy M. A. J. Geomini, Huy Ngo, Dennis van Hamont, Brenda Pijlman, M. Caroline Vos, Johan Bulten, Marc P.L.M. Snijders, Leon F.A.G. Massuger, Johanna M.A. Pijnenborg   +12 more
openalex   +1 more source

2022-RA-1499-ESGO Differential response of in-vitro mismatch repair-deficient hypermethylated endometrioid endometrial cancer models to DNA-hypomethylating agents [PDF]

, 2022
Louis Y. El Khoury, Wan Hsin Lin, James B. Smadbeck, Dorsay Sadeghian, John C. Cheville, Faye R. Harris, Lindsey Kinsella, Marina Walther Antonio, Giuseppe Cucinella, Gabriella Schivardi, Alexa McCune, Giannoula Karagouga, Aaron S. Mansfield, Andrea Mariani, George Vasmatzis, Panos Z. Anastasiadis, S. John Weroha, Alyssa Larish   +17 more
openalex   +1 more source

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

British Journal of Clinical Pharmacology, EarlyView.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao, Junjie Ding, Jiajia Zhao, Ling Zhang, Aburough Abegesah, Yu‐qian Zhang, Cathy O'Brien, Gary J. Doherty, Allen C. Chen, KyoungSoo Lim, Song Ren, Peiming Ma, Diansong Zhou   +12 more
wiley   +1 more source

Management of Endometrial Cancer

International Journal of Translation & Community Medicine, 2013
Endometrial cancer (EC) is the most common malignancy of the female genital tract.1 It occurs primarily in postmenopausal women. Overall, about 2.64% of women develop EC during their lifetime. In those patients, the most common presenting symptom is abnormal uterine bleeding. Based on clinical and pathological features, sporadic EC is classified into 2
Androutsopoulos G, Decavalas G
openaire   +1 more source

Mapping Collective Forces of Lung Cancer Spheroids Using Traction Force Microscopy

Biotechnology and Bioengineering, EarlyView.
The application of conventional TFM to cancer spheroids revealed not only a size‐dependent traction force when spheroids were in non‐wetting transition state, but also a positive correlation of this force with the spheroid dispersion capacity. Moreover, the onset of spheroid dispersion was accompanied by a pronounced suppression of spheroid traction ...
Qing Zhang, Jiaqi Chen, Zhaoxu Zhang, Weili Liu   +3 more
wiley   +1 more source

Post-transcriptional Regulation of MMP16 and TIMP2 Expression via miR-382, miR-410 and miR-200b in Endometrial Cancer [PDF]

, 2017
Beata Rak, Dawid Mehlich, Filip Garbicz, Zofia Domosud, Wiktor Paskal, Janina Marczewska, Paweł Włodarski   +6 more
openalex   +1 more source

The role of myeloid-derived suppressor cells in endometrial cancer displaying systemic inflammatory response: clinical and preclinical investigations

OncoImmunology, 2019
Systemic inflammatory responses including thrombocytosis, leukocytosis, or neutrophilia have gained attention as prognostic indicators in patients with various solid malignancies.current study, we aimed to investigate the clinical implications and ...
Eriko Yokoi, Seiji Mabuchi, Naoko Komura, Kotaro Shimura, Hiromasa Kuroda, Katsumi Kozasa, Ryoko Takahashi, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura   +13 more
doaj   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source