Results 171 to 180 of about 131,241 (336)

Long‐term outcomes of fertility‐sparing treatment in endometrial carcinoma and endometrial intraepithelial neoplasia: Recurrence risk factors over a 9‐year follow‐up

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Fertility‐sparing treatment demonstrated a 62.5% recurrence rate at 10 years. Recurrence was more likely in patients initially treated with megestrol acetate or those with a family history of cancer. As most patients lacked high‐risk molecular features, conservative treatment may remain a safe option for selected individuals under close long‐term ...
Ya‐Ting Hsu   +4 more
wiley   +1 more source

Mutations of the β‐Catenin Gene in Endometrial Carcinomas [PDF]

open access: hybrid, 1999
Kanji Kobayashi   +4 more
openalex   +1 more source

A study of oral metformin for the intravesical treatment of non‐muscle‐invasive bladder cancer

open access: yesBJU International, EarlyView.
Objectives To evaluate the effect of metformin on non‐muscle‐invasive bladder cancer (NMIBC) marker lesions. Patients and methods A phase II, open‐label, multicentre, marker lesion trial using oral metformin in patients with primary or recurrent, multiple, low‐grade Ta‐T1 NMIBC was conducted. After transurethral resection for histological confirmation,
Jons W. van Hattum   +12 more
wiley   +1 more source

A comparison of proliferation markers and their prognostic value for women with endometrial carcinoma: Ki-67, proliferating cell nuclear antigen, and flow cytometric S-phase fraction [PDF]

open access: bronze, 1996
Britta Nordström   +4 more
openalex   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Multi-omics analysis of the anti-cancer effects of curcumol in endometrial carcinoma. [PDF]

open access: yesFront Pharmacol
Xie J   +6 more
europepmc   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

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