Results 181 to 190 of about 729,992 (290)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2188-2202, September 2026.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Eisenmenger syndrome and endometrial carcinoma: a cardio-oncologic therapeutic dilemma: case report. [PDF]

open access: yesEur Heart J Case Rep
Sicupira Lima MH   +7 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Deep learning auto‐contouring of target and organs‐at‐risk on post‐catheter implant CT images for prostate HDR brachytherapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background Accurate delineation of the prostate and surrounding organs‐at‐risk (OARs) is essential for HDR prostate brachytherapy. Manual contouring on post‐catheter CT images is time‐consuming and prone to variability due to artifacts and anatomical deformation from the implanted brachytherapy catheters.
Eric M. Wallat   +5 more
wiley   +1 more source

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