Results 181 to 190 of about 143,561 (278)

Bilateral Idiopathic Pyoderma Gangrenosum: A Case Report of an Atypical Presentation

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Pyoderma gangrenosum (PG) is a rare non‐infectious neutrophilic dermatosis which is characterized by a rapidly progressive, painful ulcer. Bilateral manifestation of PG is exceptionally rare and can easily be misdiagnosed as infection or vascular ulceration, delaying proper treatment.
Sanjog Thapa Magar   +4 more
wiley   +1 more source

Minimal residual disease in solid tumors: Clinical applications and future directions

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Minimal residual disease (MRD) refers to the presence of residual cancer cells or tumor‐derived fragments that persist after treatment and remain undetectable by conventional imaging or protein‐based assays. Circulating tumor DNA (ctDNA) has emerged as a dynamic biomarker for MRD detection.
Theresa Abdo   +8 more
wiley   +1 more source

Distinct genomic subgroups and mutational patterns in undifferentiated/dedifferentiated endometrial carcinoma. [PDF]

open access: yesBMC Cancer
Huang CY   +8 more
europepmc   +1 more source

Validation of on‐slide immunocytochemistry controls prepared from long‐term preserved prefixed cell suspensions

open access: yesCancer Cytopathology, Volume 134, Issue 2, February 2026.
Abstract Background On‐slide controls are essential for quality assurance in immunocytochemistry, yet their use in non–cell block cytology preparations remains a significant challenge. This study presents and evaluates a novel method for preparing on‐slide controls from long‐term prefixed cell suspensions, applicable to all types of cytology ...
Rúben Rodrigues Roque   +6 more
wiley   +1 more source

Targeting the SIRT1‐NAT10‐GABABR1 Axis: A Novel Epitranscriptomic Approach to Mitigate Sevoflurane‐Induced Cognitive Impairment in Aging

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The study reveals that NAT10 enhances GABABR1 mRNA stability via ac4A modification, leading to excessive inhibitory synaptic activation. In aged rats, sevoflurane contributes to cognitive impairment by inhibiting Sirt1 and neuronal autophagy, which subsequently disrupts energy metabolism.
Xin Xie   +3 more
wiley   +1 more source

The involvement of lncRNA EMSLR in the disulfidptosis and progression of endometrial carcinoma. [PDF]

open access: yesCancer Gene Ther
Sun Y   +8 more
europepmc   +1 more source

GPR183‐mediated activation of PI3K is a potential biomarker for immunotherapy in lung cancer

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Anti‐PD1 treatment and PI3Kγ inhibition had remarkable therapeutic performance on CD4+ Tcm and CD4+ Tn in lung cancer through potential regulation of PI3K pathway with participation of GPR183. Abstract Background As one of commonly used immune checkpoint inhibition therapies, PD1 monoclonal antibodies exhibit a promising cancer immunotherapy approach ...
Ling Ye   +9 more
wiley   +1 more source

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