Results 211 to 220 of about 143,561 (278)

Beyond olfaction: New insights into human odorant binding proteins

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Until today, the exact function of mammalian odorant binding proteins (OBPs) remains a topic of debate. Although their main established function lacks direct evidence in human olfaction, OBPs are traditionally believed to act as odorant transporters in the olfactory sense. Now, available RNA‐seq and proteomics data identified the expression of
Mifen Chen   +5 more
wiley   +1 more source

Diagnostic and Prognostic Value of cfDNA Concentration and Fragmentation in Prostate Cancer

open access: yesThe Prostate, Volume 86, Issue 3, Page 338-348, February 15, 2026.
ABSTRACT Objective To evaluate the value of circulating free DNA (cfDNA) in prostate cancer (PCa) by cfDNA assay and analysis of plasma and urinary cfDNA fragmentation to determine the usefulness of this parameter for risk staging and tumor progression monitoring.
Marta Victoria Lorenzo‐Sánchez   +8 more
wiley   +1 more source

A Model‐Based Meta‐Analysis of Pembrolizumab Effects on Patient‐Reported Quality of Life: Advancing Patient‐Centered Oncology Drug Development

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Pembrolizumab is an immune checkpoint inhibitor that has been approved for more than 20 different indications and has shown great survival benefits in various types of cancer. However, the reported benefits of pembrolizumab in patients' quality of life (QoL) have been inconsistent across different studies and different types of cancer.
Yiqin Zou   +4 more
wiley   +1 more source

When the bones speak: A case of endometrial carcinoma metastasis. [PDF]

open access: yesRadiol Case Rep
Maslouhi K   +7 more
europepmc   +1 more source

Blurring the Lines: Co‐Occurrence of MSH6 Variant and MLH1 Constitutional Epimutation in a Young Colorectal Cancer Patient

open access: yesClinical Genetics, Volume 109, Issue 2, Page 363-367, February 2026.
We report a unique case of early‐onset colorectal cancer with both a germline MSH6 variant and constitutional mosaic MLH1 epimutation, revealing a possible digenic mechanism underlying Lynch syndrome. This case highlights the diagnostic complexity of mismatch repair deficiency and the value of integrative tumor–germline molecular profiling.
Aasem Abu Shtaya   +7 more
wiley   +1 more source

Exploring the Impact of Obesity on Progression and Prognosis in Early-Stage Endometrioid Endometrial Carcinoma. [PDF]

open access: yesWomens Health Rep (New Rochelle)
Wang J   +10 more
europepmc   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy