Intrinsic PDL1 Signaling Modulates TGFBI‐Mediated Growth Suppression in Lung Adenocarcinoma
Programmed death ligand 1 (PDL1) is known for suppressing T‐cell immunity, but its intrinsic role in oncogenesis remains unclear. This study demonstrates that PDL1 expression in lung adenocarcinoma (ADC) inhibits tumor cell growth by reducing FAK activation and regulating the CITED2‐p21CIP1 axis, leading to cell growth arrest.
Thi Thanh Nha Nguyen+6 more
wiley +1 more source
Cyclin D2 - a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis. [PDF]
Wang L, Qu W, Yang Z.
europepmc +1 more source
PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma [PDF]
Helga B. Salvesen+6 more
openalex +1 more source
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan+14 more
wiley +1 more source
Assessment of NUDT5 in Endometrial Carcinoma: Functional Insights, Prognostic and Therapeutic Implications. [PDF]
Yu H+7 more
europepmc +1 more source
CD105 (Endoglin) Expression as a Prognostic Marker in Aggressive Papillary Thyroid Carcinoma
ABSTRACT Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy, with a generally favourable prognosis. However, a subset of PTC cases exhibit aggressive behaviour, including lymph node and distant organ metastases. Identifying biomarkers that can differentiate between benign and malignant lesions, as well as predict
İlker Çordan, Tuğba Günler
wiley +1 more source
Updated Guidelines for the Diagnosis and Treatment of Endometrial Carcinoma: The Polish Society of Gynecological Oncology (2025v). [PDF]
Sznurkowski JJ+11 more
europepmc +1 more source
Using haplotype analysis, we characterized PMS2 c.2117del, identified in 22 families, as a founder variant in the French‐Canadian population of Quebec. It is the most frequent cancer‐associated founder variant in French‐Canadians, with over‐representation in five regions of Quebec. The variant contributed to colorectal and endometrial cancer incidence.
Anne‐Laure Chong+15 more
wiley +1 more source
Sentinel lymph node biopsy in low- and intermediaterisk endometrial carcinoma. [PDF]
Iavazzo C, Gkegkes ID.
europepmc +1 more source