Results 31 to 40 of about 127,260 (361)

Downregulation of tyrosine threonine kinase inhibits tumor growth via G2/M arrest in human endometrioid endometrial adenocarcinoma

open access: yesTumor Biology, 2017
Endometrial cancer is the most common gynecologic malignancy, about 80% of which is endometrial endometrioid carcinoma. Dysregulation of spindle assembly checkpoint plays a vital role in endometrial endometrioid carcinoma tumorigenesis and progression ...
Jiamiao Zhang   +6 more
doaj   +1 more source

Comparison of immunohistochemical characteristics of prognostic markers expression in non-metastatic and metastatic invasive endometrioid endometrial carcinoma

open access: yesZaporožskij Medicinskij Žurnal, 2016
Endometrial cancer occupies the sixth place among oncological morbidity structure in women worldwide. The aim. To compare the expression levels of estrogene receptors – α and progesterone receptors, regulatory proteins p16 and p53, a marker of ...
A. V. Chepets
doaj   +1 more source

LINC00665 enhances tumorigenicity of endometrial carcinoma by interacting with high mobility group AT-hook 1

open access: yesCancer Cell International, 2021
Background Endometrial carcinoma is a frequently diagnosed cancer among females. LncRNAs are reported to be associated with various cancers. Their biological roles in endometrial carcinoma progression is an emerging scientific area. LINC00665 can exert a
Yixuan Cai, Min Hao, Yue Chang, Yun Liu
doaj   +1 more source

Computer-aided diagnosis in histopathological images of the endometrium using a convolutional neural network and attention mechanisms [PDF]

open access: yesIEEE Journal of Biomedical and Health Informatics, 2020, 26(6): 1664-1676, 2019
Uterine cancer, also known as endometrial cancer, can seriously affect the female reproductive organs, and histopathological image analysis is the gold standard for diagnosing endometrial cancer. However, due to the limited capability of modeling the complicated relationships between histopathological images and their interpretations, these computer ...
arxiv   +1 more source

Mutations and amplification of oncogenes in endometrial cancer [PDF]

open access: yes, 1999
Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang   +5 more
core   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä   +18 more
wiley   +1 more source

Immunohistochemical Study of ER, PR, Ki67 and p53 in Endometrial Hyperplasias and Endometrial Carcinomas [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Introduction: Endometrial carcinoma is the second most common gynecologic malignancy in the developing countries. Endometrial Hyperplasia (EH) is a precursor to Endometrioid Adenocarcinoma (EMAC). A 23% of Atypical Hyperplasias (AEH) progress to EMAC.
Nayar Musfera Abdul Masjeed   +4 more
doaj   +1 more source

Vision Transformer-Based Deep Learning for Histologic Classification of Endometrial Cancer [PDF]

open access: yesarXiv, 2023
Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial cancer is important for effective patient management and determining the best treatment modalities.
arxiv  

Systematic assessment of HER2/neu in gynecologic neoplasms, an institutional experience. [PDF]

open access: yes, 2016
BackgroundHER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti ...
Apple, Sophia K   +5 more
core   +2 more sources

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

open access: yes, 2006
We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C.   +15 more
core   +4 more sources

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