Results 91 to 100 of about 679 (269)

Interview with the World Class Authorities Frontiers of Cancer Research: An exclusive interview with Professor Luis Diaz

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This is the second installment in the series, “The Interview with the World‐Class Authorities.” We are honored to welcome Prof. Luis Diaz, the Director of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center and Editor‐in‐Chief of Cancer Discovery. Prof.
Haruna Takeda   +4 more
wiley   +1 more source

Znaczenie polimorfizmu pojedynczych nukleotydów Arg399Gln genu XRCC1 w raku endometrium u polskich kobiet w wieku pomenopauzalnym

open access: yesMenopause Review, 2011
Background: Endometrial cancer is one of the most common malignant neoplasms which appear in the uterine body. X-ray repair cross-complementing 1 (XRCC1) protein can be involved in the repair of DNA lesions, which are known to contribute to endometrial ...
Hanna Romanowicz-Makowska   +5 more
doaj  

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

A Case Report of the Synchronous Occurrence of Ovarian Granulosa Cell Tumour and Malignant Endometrial Polyp with Immunohistochemical Expression of Hormone Receptors and Biomarkers p-53 and Ki-67

open access: yesReports
Background and Clinical Significance: Abnormal uterine bleeding during the postmenopausal years is a pathological sign that may be due to simultaneous intrauterine and ovarian pathology.
Krum Vladov   +6 more
doaj   +1 more source

Functional Characterization of a Genetic Variant in the 5′ UTR of APC 1B Promoter in a Familial Adenomatous Polyposis Family

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic germline variants in the APC gene result in familial adenomatous polyposis (FAP) which can escalate into colon cancer. Standard clinical testing failed to identify pathogenic variants in a 4‐generation FAP family. We identified and assessed co‐segregation of a 5′ untranslated region (UTR) variant, NM_001127511.3 (APC) c.‐40G>A ...
Brendon Young   +9 more
wiley   +1 more source

Clinical Insights Into Nabais Sá‐De Vries Syndrome due to a Novel SPOP Mutation: Neuromotor, Cognitive, Adaptive, Behavioral, and Neurovisual Features

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nabais Sá‐De Vries syndrome (NSDVS) is an extremely rare autosomal dominant disorder caused by SPOP mutations. To date, only 10 cases have been described presenting with intellectual disability, neurological signs and symptoms, and a variable association of dysmorphic features.
Jessica Galli   +10 more
wiley   +1 more source

A radiological complete response to pembrolizumab in a patient with metastatic upper urinary tract urothelial cancer and Lynch syndrome

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 33-36, January 2023., 2023
Introduction In Lynch syndrome, urothelial cancer is the third most common cancer, following colorectal and endometrial cancers. Little is known, however, about the efficacy of immune checkpoint inhibitors in the treatment of metastatic urothelial cancer in Lynch syndrome.
Ryosuke Oki   +7 more
wiley   +1 more source

Primary endometrial large cell neuroendocrine carcinoma with melanocytic differentiation

open access: yesAutopsy and Case Reports, 2018
High-grade endometrial carcinomas are aggressive neoplasms of difficult histological classification. Neuroendocrine differentiation in endometrial carcinomas is rare.
Lucinda Calheiros Guimarães   +3 more
doaj  

The Optimal Analgesic Method in Endometrial Sampling: Comparison of 4 Most Applied Methods Against Placebo

open access: yesSouthern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]Operations performed with only local anesthesia may be extremely painful and discomfortable for patients. The present study aims to investigate the optimal analgesic method in endometrial sampling and fractional curettage procedures ...
Halim Ömer Kaşıkçı   +6 more
doaj   +1 more source

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