Results 131 to 140 of about 83,626 (295)

The cervico-vaginal DNA methylation WID-qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer. [PDF]

Int J Cancer
What's New? The DNA methylation‐based WID‐qEC test has been validated for the accurate detection of endometrial and cervical cancers using cervico‐vaginal samples. However, a small proportion of women test positive despite the absence of these cancers. This study explored the associated biological and clinical characteristics to inform potential follow‐
Redl E, Herzog C, Vavourakis C, Barrett J, Jones A, Evans I, Reisel D, Manchanda R, Bjørge L, Zikan M, Cibula D, Alkasalias T, Rådestad AF, Gemzell-Danielsson K, Dubeau L, MacDonald N, Jurkovic D, Pashayan N, Widschwendter M.   +18 more
europepmc   +2 more sources

Whole‐Genome Bisulfite Sequencing Identifies Blood‐Based DNA Methylation Biomarker for Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Functional DNA methylation abnormalities are a hallmark of human cancers and may be a promising biomarker for their early diagnosis. Moreover, the largest methylation differences can improve the sensitivity of noninvasive diagnoses of solid tumors.
Junsheng Zhao, Sijia Shen, Junjie Zhang, Ying Xu, Jing Peng, Hainv Gao, Lanjuan Li   +6 more
wiley   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Real‐World Weight Loss Is Associated With a Reduction in Cancer Risk

Obesity, EarlyView.
ABSTRACT Objective Obesity is a major risk factor for multiple cancers, yet the impact of nonsurgical weight loss on cancer risk remains uncertain. Our objective was to evaluate whether real‐world nonsurgical weight loss is associated with a reduced risk of developing cancer.
Kenda Alkwatli, Huijun Xiao, Arshiya Mariam‐Smith, Nerea Lopetegui, Marcio L. Griebeler, Bartolome Burguera, Kevin M. Pantalone, Daniel M. Rotroff   +7 more
wiley   +1 more source

374 Uterine Tumor Resembling Ovarian Sex Cord Tumor Mimicking High-Grade Endometrial Neoplasm: A Case Report [PDF]

openalex   +1 more source

Radiomics‐based ultrasOund Model for differentiating Uterine Sarcomas from leiomyomas (ROMUS): a retrospective pilot Multicenter Italian Trials in Ovarian Cancer (MITO) study

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To develop machine‐learning models that incorporate clinical information and radiomics features extracted from ultrasound images to distinguish uterine sarcomas from leiomyomas. Methods This retrospective, multicenter, pilot case–control study included 200 patients (100 with a uterine sarcoma and 100 with a usual‐type leiomyoma, i.e.
F. Ciccarone, A. Rizzi, A. Biscione, G. Baldassari, E. H. Tran, T. Pasciuto, F. Moro, G. Zinicola, F. Buonomo, M. Colombin, F. Ghezzi, J. Casarin, R. Mancari, F. Borella, A. Kardhashi, M. Roccio, L. Savelli, R. Cioffi, F. Fanfani, G. Ferrandina, G. Scambia, L. Valentin, D. Lorusso, A. C. Testa   +23 more
wiley   +1 more source

Paraneoplastic Pulmonary Embolism Revealing Metastatic Uterine Carcinosarcoma. [PDF]

Case Rep Oncol Med
Tayar E, Bitar A, Ibrahim M.
europepmc   +1 more source

Renal cell carcinoma with atypical omental metastasis: A case report and literature review

UroPrecision, EarlyView.
Abstract Background Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, with common metastatic sites including the lungs, bones, liver, and brain. Omental metastasis is exceedingly rare and usually occurs postoperatively. Fumarate hydratase‐deficient (FH‐deficient) RCC, a recently classified and highly aggressive subtype of ...
Andrew Jing, Zachary Guo, Katherine Wu, Wei Wang, James Jing   +4 more
wiley   +1 more source

Undifferentiated endometrial carcinoma: a case report. [PDF]

J Med Case Rep
Gu Z, Tang Q, Lu S.
europepmc   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source